| Autor: |
Manap HH; Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603, Kuala Lumpur, Malaysia., Abdul Wahab AK; Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, 50603, Kuala Lumpur, Malaysia. khairi@um.edu.my.; Centre for Separation Science and Technology (CSST), Department of Chemical Engineering, Faculty of Engineering, University of Malaya, 50603, Kuala Lumpur, Malaysia. khairi@um.edu.my. |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs [J Artif Organs] 2017 Mar; Vol. 20 (1), pp. 8-17. Date of Electronic Publication: 2016 May 18. |
| DOI: |
10.1007/s10047-016-0905-x |
| Abstrakt: |
The implementation of extracorporeal carbon dioxide removal (ECCO 2 R) as one of the extracorporeal life support system is getting more attention today. Thus, the objectives of this paper are to study the clinical practice of commercial ECCO 2 R system, current trend of its development and also the perspective on future improvement that can be done to the existing ECCO 2 R system. The strength of this article lies in its review scope, which focuses on the commercial ECCO 2 R therapy in the market based on membrane lung and current investigation to improve the efficiency of the ECCO 2 R system, in terms of surface modification by carbonic anhydrase (CA) immobilization technique and respiratory electrodialysis (R-ED). Our methodology approach involves the identification of relevant published literature from PubMed and Web of Sciences search engine using the terms Extracorporeal Carbon Dioxide Removal (ECCO 2 R), Extracorporeal life support, by combining terms between ECCO 2 R and CA and also ECCO 2 R with R-ED. This identification only limits articles in English language. Overall, several commercial ECCO 2 R systems are known and proven safe to be used in patients in terms of efficiency, safety and risk of complication. In addition, CA-modified hollow fiber for membrane lung and R-ED are proven to have good potential to be applied in conventional ECCO 2 R design. The detailed technique and current progress on CA immobilization and R-ED development were also reviewed in this article. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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