Serological Prevalence of Leptospirosis Among Rural Communities in the Rejang Basin, Sarawak, Malaysia.

Autor: Suut L; Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia slela@unimas.my., Mazlan MN; Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia., Arif MT; Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia., Yusoff H; Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia., Abdul Rahim NA; Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia., Safii R; Universiti Malaysia Sarawak, Kota Samarahan, Sarawak, Malaysia., Suhaili MR; SEGi University, Sibu, Sarawak, Malaysia.
Jazyk: angličtina
Zdroj: Asia-Pacific journal of public health [Asia Pac J Public Health] 2016 Jul; Vol. 28 (5), pp. 450-7. Date of Electronic Publication: 2016 May 16.
DOI: 10.1177/1010539516648003
Abstrakt: Leptospirosis is an important zoonotic disease globally and is endemic in Malaysia. A study was conducted in the Rejang basin of Sarawak from June 2011 to May 2013 to determine the seroprevalence of leptospirosis among the communities and dominant infecting Leptospira serovars. A total of 508 human sera were analyzed using ELISA and the microscopic agglutination test (MAT). The seroprevalence of leptospirosis in the study area was 37.4%, with the highest prevalence in Kapit division. More women were positive for leptospirosis (59.5%), and the mean age of seropositive individuals was 42.2 (SD = 18.7) years. Antibody titers between 1:50 and 1:1600 were reported, and serovars djasiman (22.1%), shermani (13.2%), and pomona (7.9%) predominated, with varied distribution between geographical locations. This study highlighted the endemicity and diversity of existing Leptospira serovars within the community. This information should be communicated to local health personnel and communities at risk, and rapid diagnostic capability should be made available to local health facilities.
(© 2016 APJPH.)
Databáze: MEDLINE