In Situ Melanoma of the Gingiva Associated with Dense Inflammation and Pigment Deposition: A Potential Diagnostic Pitfall in Evaluating Stromal Invasion.

Autor: Sedassari BT; School of Dentistry, Oral and Maxillofacial Pathology, University of São Paulo, São Paulo, Brazil., Lascane NA; School of Dentistry, Stomatology, Santa Cecília University, Rua Oswaldo Cruz, Santos, SP, CEP: 11045-907, Brazil. ne_lascane@hotmail.com., de Freitas AL; School of Dentistry, Stomatology, Santa Cecília University, Rua Oswaldo Cruz, Santos, SP, CEP: 11045-907, Brazil., Mautoni MC; School of Dentistry, Stomatology, Santa Cecília University, Rua Oswaldo Cruz, Santos, SP, CEP: 11045-907, Brazil., Sotto MN; School of Medicine, Dermatopathology, University of São Paulo, São Paulo, Brazil., Gallottini MH; School of Dentistry, Oral and Maxillofacial Pathology, University of São Paulo, São Paulo, Brazil., de Sousa SC; School of Dentistry, Oral and Maxillofacial Pathology, University of São Paulo, São Paulo, Brazil., Pinto DD Jr; School of Dentistry, Oral and Maxillofacial Pathology, University of São Paulo, São Paulo, Brazil.
Jazyk: angličtina
Zdroj: Head and neck pathology [Head Neck Pathol] 2016 Dec; Vol. 10 (4), pp. 547-551. Date of Electronic Publication: 2016 May 13.
DOI: 10.1007/s12105-016-0728-3
Abstrakt: Melanoma is a highly aggressive neoplasm in which the neoplastic cells display melanocytic differentiation. Less than 1 % of all melanomas arise in the mucosal surfaces of the oral cavity, with purely in situ lesions being exceedingly rare tumors, but with a favorable prognosis compared with invasive lesions. We describe the clinical, histopathological and immunohistochemical findings in an uncommon case of in situ mucosal melanoma of the oral cavity with intense tumor-associated pigment deposition and inflammation complicating the morphological assessment of infiltrative areas.
Competing Interests: No conflict of interest to disclose.
Databáze: MEDLINE
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