Malaria Transmission Under an Unusual Circumstance Causing Death in Two Siblings.

Autor:	Dayanand KK; Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania. Department of Biochemistry, Kuvempu University, Shivamogga, Karnataka, India., Punnath K; Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania., Chandrashekar VN; Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania., Kakkilaya SB; Light House Polyclinic, Spandana Center for Metabolic Medicine, Mangalore, Karnataka, India., Ghosh SK; National Institute of Malaria Research, Bangalore Field Station, ICMR Complex, Bangalore, Karnataka, India., Tiwari SN; National Institute of Malaria Research, Bangalore Field Station, ICMR Complex, Bangalore, Karnataka, India., Achur RN; Department of Biochemistry, Kuvempu University, Shivamogga, Karnataka, India., Kadambi SS; Directorate of Health and Family Welfare Services, Government of Karnataka, Bangalore, Karnataka, India., Gowda DC; Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey, Pennsylvania. gowda@psu.edu.
Jazyk:	angličtina
Zdroj:	The American journal of tropical medicine and hygiene [Am J Trop Med Hyg] 2016 Jul 06; Vol. 95 (1), pp. 155-7. Date of Electronic Publication: 2016 May 02.
DOI:	10.4269/ajtmh.16-0082
Abstrakt:	Two school-going siblings from a family residing in a presumed malaria non-endemic locality ∼90 km from Mangalore city in southwestern India contracted Plasmodium falciparum infection. In both cases, misunderstanding of initial clinical symptoms as due to viral hepatitis resulted in progression to severe malaria before malaria treatment was initiated. Despite treatment at a tertiary hospital, the children died of cerebral malaria and multi-organ dysfunction. Active case detection in the affected locality suggested that the infection was transmitted from infected individuals who worked in nearby malaria-endemic areas and periodically visited their families. A lesson from this study is that lethal falciparum malaria can be transmitted in regions of India, believed to be non-endemic for the disease, resulting in fatal outcomes if diagnosis is missed or delayed. Implementation of effective surveillance and control measures as well as preparedness for malaria detection and diagnosis are necessary in areas that are potentially disposed to malaria transmission even though they are presumed to be non-endemic. (© The American Society of Tropical Medicine and Hygiene.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu