Severity of erectile dysfunction is highly correlated with the syntax score in patients undergoing coronariography.

Autor:	Andrade WS; Universidade Federal de Sergipe, Aracaju, Sergipe, Brasil., Oliveira P; Universidade Estadual de Feira de Santana, Feira de Santana, Bahia, Brasil., Laydner H; University Hospitals-Urology, Cleveland, OH, USA., Ferreira EJ; Universidade Federal de Sergipe, Aracaju, Sergipe, Brasil., Barreto-Filho JA; Universidade Federal de Sergipe, Aracaju, Sergipe, Brasil.
Jazyk:	angličtina
Zdroj:	International braz j urol : official journal of the Brazilian Society of Urology [Int Braz J Urol] 2016 Jan-Feb; Vol. 42 (1), pp. 123-31.
DOI:	10.1590/S1677-5538.IBJU.2015.0002
Abstrakt:	Objective: To investigate the association between the severity of erectile dysfunction (ED) and coronary artery disease (CAD) in men undergoing coronary angiography for angina or acute myocardial infarct (AMI). Material and Methods: We studied 132 males who underwent coronary angiography for first time between January and November 2010. ED severity was assessed by the international index of erectile function (IIEF-5) and CAD severity was assessed by the Syntax score. Patients with CAD (cases) and without CAD (controls) had their IIEF-5 compared. In the group with CAD, their IIEF-5 scores were compared to their Syntax score results. Results: We identified 86 patients with and 46 without CAD. The IIEF-5 score of the group without CAD (22.6±0.8) was significantly higher than the group with CAD (12.5±0.5; p<0.0001). In patients without ED, the Syntax score average was 6.3±3.5, while those with moderate or severe ED had a mean Syntax score of 39.0±11.1. After adjustment, ED was independently associated to CAD, with an odds ratio of 40.6 (CI 95%, 14.3-115.3, p<0.0001). The accuracy of the logistic model to correctly identify presence or absence of CAD was 87%, with 92% sensitivity and 78% specificity. The average time that ED was present in patients with CAD was 38.8±2.3 months before coronary symptoms, about twice as high as patients without CAD (18.0±5.1 months). Conclusions: ED severity is strongly and independently correlated with CAD complexity, as assessed by the Syntax score in patients undergoing coronariography for evaluation of new onset coronary symptoms.
Databáze:	MEDLINE
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