Initial Outcomes of a Lung Cancer Screening Program in an Integrated Community Health System.

Autor:	Miller AT; Department of Internal Medicine, Intermountain Medical Center, Murray, Utah., Kruger P; Division of Oncology, Intermountain Medical Center, Murray, Utah., Conner K; Department of Radiology, Intermountain Medical Center, Murray, Utah., Robertson T; Clinical Information Systems, Intermountain Medical Center, Murray, Utah., Rowley B; Clinical Information Systems, Intermountain Medical Center, Murray, Utah., Sause W; Division of Radiation Oncology, Intermountain Medical Center, Murray, Utah., Ruckdeschel JC; Division of Oncology, Intermountain Medical Center, Murray, Utah; Synergy Cancer Center, Las Vegas, Nevada., Blagev DP; Division of Pulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, Utah; Division of Pulmonary and Critical Care Medicine, University of Utah, Salt Lake City, Utah. Electronic address: denitza.blagev@imail.org.
Jazyk:	angličtina
Zdroj:	Journal of the American College of Radiology : JACR [J Am Coll Radiol] 2016 Jun; Vol. 13 (6), pp. 733-7. Date of Electronic Publication: 2016 Apr 28.
DOI:	10.1016/j.jacr.2016.02.013
Abstrakt:	Purpose: Lung cancer screening with low-dose CT (LDCT) demonstrated reduced mortality in the National Lung Screening Trial, yet there is debate as to whether the reported efficacy can translate into comparable effectiveness with community-based screening. The authors' purpose is to report the baseline patient characteristics and malignancy rate in the first 18 months after implementing a lung cancer screening program in an integrated community health system. Methods: Patients were screened at 1 of 10 participating community-based centers within a 22-hospital system from 2013 to 2015. LDCT examinations were interpreted by 1 of 20 radiologists using structured reporting and an internally developed tracking system. Manual chart review was performed to ascertain the malignancy detection rate. Results: A total of 357 patients were screened with LDCT. Of these, 80 patients were ineligible and 3 declined enrollment. The remaining 274 patients satisfied accepted screening criteria and were enrolled in the program. Malignancy was detected in a total of 11 enrollees (4.0%), 8 with lung cancer and 3 with extrapulmonary primary malignancies. Three patients (1.1%) were diagnosed with early-stage lung cancer and received definitive therapy. Conclusions: Early-stage lung cancer was detected with LDCT screening in an integrated community health system at a rate similar to other trials. (Copyright © 2016 American College of Radiology. Published by Elsevier Inc. All rights reserved.)
Databáze:	MEDLINE
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