Long-term drug-resistant temporal lobe epilepsy associated with a mixed ganglioglioma and dysembryoplastic neuroepithelial tumor in an elderly patient.

Autor:	Schijns OE; Department of Neurosurgery, Maastricht University Medical Center, Maastricht, The Netherlands; Department of School of Mental Health and Neurosciences, School of Mental Health and Neurosciences, Maastricht University, Maastricht, The Netherlands; Academic Center for Epileptology, Maastricht University Medical Center, Maastricht, The Netherlands., Beckervordersandforth J; Department of Pathology, Maastricht University Medical Center, Maastricht, The Netherlands., Wagner L; Department of Epileptology, Academic Center for Epileptology, Kempenhaeghe, Heeze, The Netherlands., Hoogland G; Department of Neurosurgery, Maastricht University Medical Center, Maastricht, The Netherlands; Department of School of Mental Health and Neurosciences, School of Mental Health and Neurosciences, Maastricht University, Maastricht, The Netherlands.
Jazyk:	angličtina
Zdroj:	Surgical neurology international [Surg Neurol Int] 2016 Apr 01; Vol. 7 (Suppl 9), pp. S243-6. Date of Electronic Publication: 2016 Apr 01 (Print Publication: 2016).
DOI:	10.4103/2152-7806.179583
Abstrakt:	Background: Mixed ganglioglioma and dysembryoplastic neuroepithelial tumor (DNET) is an extremely rare neuropathological diagnosis. The sparse number of patients described are children or young adults with long-term drug-resistant epilepsy. Case Description: We report on a rare case of this tumor in a 61-year-old patient with an epilepsy duration of almost 60 years. This patient received an epilepsy surgery work-up with the intention to cure his drug-resistant epilepsy by performing a complete lesionectomy. The available literature on these mixed tumors is reviewed. Conclusion: A contrast-enhancing mixed ganglioglioma and DNET can mimic a malignant tumor and appears not only in children and young adults, but also in the elderly patients with chronic epilepsy. A long-lasting epilepsy, in this case almost 60 years, can be completely cured by a complete lesionectomy.
Databáze:	MEDLINE
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