Arylative Desulfonation of Diarylmethyl Phenyl Sulfone with Arenes Catalyzed by Scandium Triflate.
| Autor: | Nambo M; Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University , 464-8601 Nagoya, Japan., Ariki ZT; Department of Chemistry, Queen's University , Chernoff Hall, Kingston, Ontario K7L 3N6, Canada., Canseco-Gonzalez D; Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University , 464-8601 Nagoya, Japan., Beattie DD; Department of Chemistry, Queen's University , Chernoff Hall, Kingston, Ontario K7L 3N6, Canada., Crudden CM; Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University , 464-8601 Nagoya, Japan.; Department of Chemistry, Queen's University , Chernoff Hall, Kingston, Ontario K7L 3N6, Canada. |
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| Jazyk: | angličtina |
| Zdroj: | Organic letters [Org Lett] 2016 May 20; Vol. 18 (10), pp. 2339-42. Date of Electronic Publication: 2016 Apr 28. |
| DOI: | 10.1021/acs.orglett.6b00744 |
| Abstrakt: | A scandium-triflate-catalyzed arylative desulfonation of diarylmethyl phenyl sulfones with arenes and heteroarenes was established. A variety of both sulfone and arene substrates were reacted to afford symmetric and nonsymmetric triarylmethanes in good yields. Further transformations of the resulting triarylmethanes and application to the concise synthesis of a bactericidal agent analogue were also demonstrated. |
| Databáze: | MEDLINE |
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