Coronary Diameters in Taiwanese Children Younger than 6 Years Old: Z-Score Regression Equations Derived from Body Surface Area.

Autor: Lin MT; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University;, Chang CH; Department of Medical Research, National Taiwan University Hospital;, Hsieh WC; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University;, Chang CE; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University;, Chang YM; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University;, Chen YC; Department of Pediatrics, Cathay General Hospital;, Hsu JY; Department of Pediatrics, Buddhist Tzu-Chi General Hospital, Taipei Branch;, Huang YL; Department of Pediatrics, Wan Fang Hospital, Taipei Medical University;, Ma JY; Department of Pediatrics, Far-East Memorial Hospital;, Sun LC; Department of Pediatrics, Cardinal Tien Hospital;, Wu CS; Department of Pediatrics, Taipei City Hospital;, Yeh SZ; Department of Pediatrics, Far-East Memorial Hospital;, Fang WQ; National Translational Medicine and Clinical Trial Resource Center, Taipei, Taiwan., Chen CA; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University;, Chiu SN; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University;, Lu CW; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University;, Wang JK; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University;, Wu MH; Department of Pediatrics, National Taiwan University Hospital and College of Medicine, National Taiwan University;
Jazyk: angličtina
Zdroj: Acta Cardiologica Sinica [Acta Cardiol Sin] 2014 Jul; Vol. 30 (4), pp. 266-73.
Abstrakt: Background: The measurements of coronary diameters, usually obtained by 2-dimentsional echocardiography, play important roles oin the management and follow-up of Kawasaki disease (KD). However, in Taiwan, domestic normgrams and a Z-score calculator for coronary artery diameters are still not available.
Methods: Echocardiography was performed on 412 healthy children younger than 6 years of age. The appropriate exponential regression model was fitted to correspond with body surface area (BSA). The computed Z-scores of all subjects were also tested for normal distribution.
Results: Using the model ln (measurement) = β1 + β2 × ln (BSA), the adjusted R(2) values were 0.611 and 0.484 for the models of the left main coronary artery (LMCA) and the right (RCA), respectively. Analysis of computed Z-score distribution showed acceptable goodness of fit for a normal distribution [p = 0.90 (LMCA); p = 0.17 (RCA)].
Conclusions: We have established reference ranges for the coronary artery diameters in Taiwanese children younger than 6 years of age. The regression equations and Z-score calculators for the LMCA and RCA provide an objective determination of coronary dilatation in a large population, which is important for the care and medical management of KD patients in Taiwan.
Key Words: Coronary diameter; Kawasaki disease; Taiwan; Z-score.
Databáze: MEDLINE