Uptake, tissue distribution and depuration of triclosan in the guppy Poecilia vivipara acclimated to freshwater.

Autor: Escarrone AL; Instituto de Ciências Biológicas, Programa de Pós-graduação em Fisiologia Animal Comparada, Universidade Federal do Rio Grande, Av Itália, km8, s/n, Rio Grande, Rio Grande do Sul State 96203-900, Brazil., Caldas SS; Laboratório de Análises de Compostos Orgânicos e Metais, Escola de Química e Alimentos, Programa de Pós-graduação em Química Tecnológica e Ambiental, Universidade Federal do Rio Grande, Av Itália, km8, s/n, Rio Grande, Rio Grande do Sul State 96203-900, Brazil., Primel EG; Laboratório de Análises de Compostos Orgânicos e Metais, Escola de Química e Alimentos, Programa de Pós-graduação em Química Tecnológica e Ambiental, Universidade Federal do Rio Grande, Av Itália, km8, s/n, Rio Grande, Rio Grande do Sul State 96203-900, Brazil., Martins SE; Instituto de Ciências Biológicas, Programa de Pós-graduação em Fisiologia Animal Comparada, Universidade Federal do Rio Grande, Av Itália, km8, s/n, Rio Grande, Rio Grande do Sul State 96203-900, Brazil., Nery LE; Instituto de Ciências Biológicas, Programa de Pós-graduação em Fisiologia Animal Comparada, Universidade Federal do Rio Grande, Av Itália, km8, s/n, Rio Grande, Rio Grande do Sul State 96203-900, Brazil. Electronic address: famnery@terra.com.
Jazyk: angličtina
Zdroj: The Science of the total environment [Sci Total Environ] 2016 Aug 01; Vol. 560-561, pp. 218-24. Date of Electronic Publication: 2016 Apr 19.
DOI: 10.1016/j.scitotenv.2016.04.039
Abstrakt: The agent triclosan has been extensively used in different personal care products as a broad-spectrum antimicrobial and preservative agent. Due to its continuous release into the environment, including discharge via wastewater treatment plants, triclosan has been widely detected in aquatic environments. There is growing interest in improving the knowledge about the environmental fate of triclosan due to its possible bioaccumulation and the toxicity it may pose to organisms, such as fish and other non-target species. To investigate the distribution and bioconcentration of triclosan in fish, Poecilia vivipara was exposed to 0.2mgL(-1). Contents of triclosan in whole fish, brain, gonads, liver, muscle and gills were quantified by LC-MS/MS. When lipid normalised concentration was used, the liver exhibited the highest concentration followed by the gills, gonads, brain and muscle tissues. Bioconcentration was increased with time reaching a steady-state around 7-14days for most all tissues. After 24h depuration, triclosan concentrations declined >80% in all tissues except liver, in which triclosan takes longer to be depurated. These results not only clearly indicate that triclosan accumulated in P. vivipara, with tissue-specific bioconcentration factors (BCF) that ranged from 40.2 to 1025.4, but also show that the elimination of triclosan after transferring the fish to triclosan-free freshwater is rapid in all tissues.
(Copyright © 2016 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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