Assessment of wound bio-burden and prevalence of multi-drug resistant bacteria during open wound management.

Autor: Nolff MC; Clinic for Small Animal Surgery and Reproduction, Ludwig-Maximilians-University, Veterinärstrasse 13, Munich, 80539, Germany., Reese S; Department for Basic Veterinary Sciences, Ludwig-Maximilians-University, Professor-Huber-Platz 2, Munich, 80539, Germany., Fehr M; Small Animal Clinic, University of Veterinary Medicine of Hannover, Bünteweg 2, 30559, Hannover, Germany., Dening R; Small Animal Clinic, University of Veterinary Medicine of Hannover, Bünteweg 2, 30559, Hannover, Germany., Meyer-Lindenberg A; Clinic for Small Animal Surgery and Reproduction, Ludwig-Maximilians-University, Veterinärstrasse 13, Munich, 80539, Germany.
Jazyk: angličtina
Zdroj: The Journal of small animal practice [J Small Anim Pract] 2016 May; Vol. 57 (5), pp. 255-9. Date of Electronic Publication: 2016 Apr 21.
DOI: 10.1111/jsap.12476
Abstrakt: Objective: To describe the bacterial bio-burden of open-treated wounds and make comparisons with bite wounds.
Design: Retrospective multicentre study.
Sample: Microbial culture between 2011 and 2013 from open-treated wounds in dogs and cats (initiation of therapy n=88, follow-up n=52) were compared to those from bite wounds (n=184).
Procedures: Bacteria were identified and tested for antibiotic susceptibility by two accredited laboratories.
Results: In total, 77/88 (88%) of open-treated wounds yielded positive bacterial cultures at the beginning of treatment, decreasing to 27/52 (52%) during treatment. Upon initial evaluation, 42/88 (48 %) of open-treated wounds were considered infected with multi-drug-resistant bacteria, with a drop to 22/52 (41%) during therapy. Bite wounds yielded fewer positive cultures 88/184 (48%) with only 11/182 (6%) being affected by multi-drug-resistant bacteria. Bacteria found most commonly in open-treated wounds were Enterococcus subspecies, Escherichia coli, Staphylococcus pseudintermedius and Pseudomonas aeruginosa.
Conclusion: The bacterial populations of open-treated wounds differed markedly from the bite wounds. The high incidence of multi-drug-resistant strains in open wounds highlights the need for alternatives to antibiotics.
(© 2016 British Small Animal Veterinary Association.)
Databáze: MEDLINE
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