Clinical experience with ciprofloxacin: analysis of a multi-practice study.

Autor: Dunbar CP, Ashton RL, Atkinson L, Crotwell HF, Faris HM, Royal HG Jr, Tyson DW, White CH Jr
Jazyk: angličtina
Zdroj: Journal of the South Carolina Medical Association (1975) [J S C Med Assoc] 1989 Mar; Vol. 85 (3), pp. 97-101.
Abstrakt: In a multi-practice study of 113 patients treated with ciprofloxacin (mean daily dosage, 995 mg per day; mean duration of treatment, 9.6 days) for a variety of infections, 14 were microbiologically proven. Of these, bacteriologic cure and/or improvement resulted in 92.9% of cases. For all 113 infections, clinical cure and/or improvement resulted in 97.1% of cases. A total of 17 infections were classified as chronic. Therapy with ciprofloxacin was discontinued in three (2.6%) of 113 patients because of adverse effects. Overall, there were 5/113 (4.4%) adverse reactions (ADRs). Only one ADR was related definitely to ciprofloxacin therapy. Two ADRs were definitely not related; in two the relationship was uncertain. Two patients of the five (40%) elected to continue ciprofloxacin therapy despite mild side effects.
Databáze: MEDLINE