Free amino acids: an innovative treatment for ocular surface disease.
| Autor: | Rusciano D; Sooft Italia SpA, Scientific Department, Via Salvatore Quasimodo 136, 00144 Rome, Italy. Electronic address: dario.rusciano@sooft.it., Roszkowska AM; Cornea and Refractive Surgery Section, Ophthalmology Unit, University Hospital of Messina, Italy., Gagliano C; Ophthalmology Department, University of Catania, Catania, Italy., Pezzino S; Sooft laboratories, Viale Andrea Doria 21, 95125 Catania, Italy. |
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| Jazyk: | angličtina |
| Zdroj: | European journal of pharmacology [Eur J Pharmacol] 2016 Sep 15; Vol. 787, pp. 9-19. Date of Electronic Publication: 2016 Apr 14. |
| DOI: | 10.1016/j.ejphar.2016.04.029 |
| Abstrakt: | Amino acids are the basic constituents of living organisms, and have both a structural and an active dynamic role in tissue and cell physiology. Human tears contain 23 amino acids, the relative proportion of which may change with the different physiological states of the eye surface. In this review, we present a collection of data from the published literature that indicate an active role of amino acids in the maintenance of eye surface homeostasis. Moreover, another series of published clinical data indicate that supplementation of amino acids, either as food supplements or as a topical treatment in enriched eye drops, is beneficial to the eye surface, and may improve its healing in cases of eye surface disease due to different causes. (Copyright © 2016 Elsevier B.V. All rights reserved.) |
| Databáze: | MEDLINE |
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