Design, Synthesis, and Evaluation of Novel Auxin Mimic Herbicides.

Autor: Do-Thanh CL; Department of Chemistry, The University of Tennessee , Knoxville, Tennessee 37996, United States., Vargas JJ; Department of Plant Sciences, The University of Tennessee , Knoxville, Tennessee 37996, United States., Thomas JW; Department of Plant Sciences, The University of Tennessee , Knoxville, Tennessee 37996, United States., Armel GR; Department of Plant Sciences, The University of Tennessee , Knoxville, Tennessee 37996, United States.; Global Herbicide Development Division, BASF Corporation , Research Triangle Park, North Carolina 27709, United States., Best MD; Department of Chemistry, The University of Tennessee , Knoxville, Tennessee 37996, United States.
Jazyk: angličtina
Zdroj: Journal of agricultural and food chemistry [J Agric Food Chem] 2016 May 11; Vol. 64 (18), pp. 3533-7. Date of Electronic Publication: 2016 Apr 27.
DOI: 10.1021/acs.jafc.6b00675
Abstrakt: Due to the key roles of auxins as master regulators of plant growth, there is considerable interest in the development of compounds with auxin-like properties for growth management and weed control applications. Herein, we describe the design and multistep synthesis of ten compounds bearing combinations of functional groups commonly associated with auxin-type properties. Following synthesis, these compounds were tested against multiple weed species as well as sweet corn. In general, while these structures were not quite as active as commercial auxin mimic herbicides, multiple compounds exhibited broadleaf weed activity with concurrent selectivity in sweet corn (Zea mays L. var. saccharum). In addition, differential results were observed upon subtle changes to structure, providing insights into the structural properties required for activity.
Databáze: MEDLINE