| Autor: |
Kliment'eva TK, Sal'nik BIu, Chamina GM |
| Jazyk: |
ruština |
| Zdroj: |
Farmakologiia i toksikologiia [Farmakol Toksikol] 1989 Jan-Feb; Vol. 52 (1), pp. 71-4. |
| Abstrakt: |
Antitumour drugs prospidine and spirobromine were shown to suppress the activity of the mouse liver lysosome enzymes in vivo and in experiments in vitro. The revealed effect was underlied by a decrease of lysosomal membrane permeability for the corresponding substrates and enzymes rather than a reduction of the catalytic activity of acid hydrolases. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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