Feasibility of low-dose CT with model-based iterative image reconstruction in follow-up of patients with testicular cancer.

Autor:	Murphy KP; Department of Radiology, Cork University Hospital, Cork, Ireland; Department of Radiology, University College Cork, Cork, Ireland; Department of Radiology, Mercy University Hospital, Cork, Ireland., Crush L; Department of Radiology, University College Cork, Cork, Ireland; Department of Radiology, Mercy University Hospital, Cork, Ireland., O'Neill SB; Department of Radiology, Cork University Hospital, Cork, Ireland; Department of Radiology, Mercy University Hospital, Cork, Ireland., Foody J; Department of Electrical and Electronic Engineering, University College Cork, Cork, Ireland., Breen M; Department of Radiology, Boston Children's Hospital, 300 Longwood Avenue, Boston, MA 02115, USA., Brady A; Department of Radiology, Mercy University Hospital, Cork, Ireland., Kelly PJ; Department of Radiation Oncology, Cork University Hospital, Cork, Ireland., Power DG; Department of Medical Oncology, Cork and Mercy University Hospitals, Cork, Ireland., Sweeney P; Department of Urology, Mercy University Hospital, Cork, Ireland., Bye J; General Electric Healthcare Technologies, Herdfordshire, UK., O'Connor OJ; Department of Radiology, Cork University Hospital, Cork, Ireland; Department of Radiology, University College Cork, Cork, Ireland; Department of Radiology, Mercy University Hospital, Cork, Ireland., Maher MM; Department of Radiology, Cork University Hospital, Cork, Ireland; Department of Radiology, University College Cork, Cork, Ireland; Department of Radiology, Mercy University Hospital, Cork, Ireland., O'Regan KN; Department of Radiology, Cork University Hospital, Cork, Ireland.
Jazyk:	angličtina
Zdroj:	European journal of radiology open [Eur J Radiol Open] 2016 Feb 16; Vol. 3, pp. 38-45. Date of Electronic Publication: 2016 Feb 16 (Print Publication: 2016).
DOI:	10.1016/j.ejro.2016.01.002
Abstrakt:	Purpose: We examine the performance of pure model-based iterative reconstruction with reduced-dose CT in follow-up of patients with early-stage testicular cancer. Methods: Sixteen patients (mean age 35.6 ± 7.4 years) with stage I or II testicular cancer underwent conventional dose (CD) and low-dose (LD) CT acquisition during CT surveillance. LD data was reconstructed with model-based iterative reconstruction (LD-MBIR). Datasets were objectively and subjectively analysed at 8 anatomical levels. Two blinded clinical reads were compared to gold-standard assessment for diagnostic accuracy. Results: Mean radiation dose reduction of 67.1% was recorded. Mean dose measurements for LD-MBIR were: thorax - 66 ± 11 mGy cm (DLP), 1.0 ± 0.2 mSv (ED), 2.0 ± 0.4 mGy (SSDE); abdominopelvic - 128 ± 38 mGy cm (DLP), 1.9 ± 0.6 mSv (ED), 3.0 ± 0.6 mGy (SSDE). Objective noise and signal-to-noise ratio values were comparable between the CD and LD-MBIR images. LD-MBIR images were superior (p < 0.001) with regard to subjective noise, streak artefact, 2-plane contrast resolution, 2-plane spatial resolution and diagnostic acceptability. All patients were correctly categorised as positive, indeterminate or negative for metastatic disease by 2 readers on LD-MBIR and CD datasets. Conclusions: MBIR facilitated a 67% reduction in radiation dose whilst producing images that were comparable or superior to conventional dose studies without loss of diagnostic utility.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu