Can propolis and caffeic acid phenethyl ester be promising agents against cyclophosphamide toxicity?

Autor: Akyol S; Department of Medical Biology, Turgut Ozal University Medical Faculty, Ankara, Turkey., Gulec MA; Department of Medical Biochemistry, Faculty of Medicine, Turgut Ozal University, Ankara, Turkey., Erdemli HK; Department of Biochemistry Laboratory, Corum Training and Research Hospital, Corum, Turkey., Akyol O; Department of Medical Biochemistry, Hacettepe University Medical Faculty, Ankara, Turkey.
Jazyk: angličtina
Zdroj: Journal of intercultural ethnopharmacology [J Intercult Ethnopharmacol] 2016 Jan 28; Vol. 5 (1), pp. 105-7. Date of Electronic Publication: 2016 Jan 28 (Print Publication: 2016).
DOI: 10.5455/jice.20160127024542
Abstrakt: Propolis is a mixture having hundreds of polyphenols including caffeic acid phenethyl ester (CAPE). They have been using in several medical conditions/diseases in both in vitro and in vivo experimental setup. Cyclophosphamide (CP) has been used to treat a broad of malignancies including Hodgkin's and non-Hodgkin's lymphoma, Burkitt's lymphoma, chronic lymphocytic leukemia, Ewing's sarcoma, breast cancer, testicular cancer, etc. It may cause several side effects after treatment. In this mini review, the protective effects of propolis and CAPE were compared each other in terms of effectiveness against CP-induced injuries.
Databáze: MEDLINE