Poorly differentiated chordoma with SMARCB1/INI1 loss: a distinct molecular entity with dismal prognosis.

Autor: Hasselblatt M; Institute of Neuropathology, University Hospital Münster, Pottkamp 2, 48149, Münster, Germany. martin.hasselblatt@ukmuenster.de., Thomas C; Institute of Neuropathology, University Hospital Münster, Pottkamp 2, 48149, Münster, Germany., Hovestadt V; Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany.; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany., Schrimpf D; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany.; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Johann P; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Pediatric Oncology and Hematology, University Hospital Heidelberg, Heidelberg, Germany., Bens S; Institute of Human Genetics, Christian-Albrechts-University Kiel, Kiel, Germany., Oyen F; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Peetz-Dienhart S; Institute of Neuropathology, University Hospital Münster, Pottkamp 2, 48149, Münster, Germany., Crede Y; Institute of Neuropathology, University Hospital Münster, Pottkamp 2, 48149, Münster, Germany., Wefers A; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany.; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Vogel H; Department of Pathology, Stanford University School of Medicine, Palo Alto, CA, 94305, USA., Riemenschneider MJ; Department of Neuropathology, Regensburg University Hospital, Regensburg, Germany., Antonelli M; Department of Radiology, Oncology and Anatomic-Pathology Sciences, Sapienza University, Rome, Italy.; IRCCS Neuromed, Pozzilli, IS, Italy., Giangaspero F; Department of Radiology, Oncology and Anatomic-Pathology Sciences, Sapienza University, Rome, Italy.; IRCCS Neuromed, Pozzilli, IS, Italy., Bernardo MC; Institute of Pathology, St. Luke's Medical Center, Quezon City, Philippines., Giannini C; Department of Pathology, Mayo Clinic, Rochester, MN, USA., Ud Din N; Section of Histopathology, Department of Pathology and Laboratory Medicine, Aga Khan University Hospital, Karachi, Pakistan., Perry A; Division of Neuropathology, UCSF Medical Center, San Francisco, CA, USA., Keyvani K; Faculty of Medicine, Institute of Neuropathology, University of Duisburg-Essen, Essen, Germany., van Landeghem F; Division of Anatomical Pathology, Neuropathology Specialty Group, Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Canada., Sumerauer D; Department of Pediatric Hematology and Oncology, University Hospital Motol, Charles University, 2nd Medical School, Prague, Czech Republic., Hauser P; 2nd Department of Pediatrics, Semmelweis University, 1094, Budapest, Hungary., Capper D; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany.; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Korshunov A; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany.; Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Jones DT; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Pfister SM; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Pediatric Oncology and Hematology, University Hospital Heidelberg, Heidelberg, Germany., Schneppenheim R; Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Siebert R; Institute of Human Genetics, Christian-Albrechts-University Kiel, Kiel, Germany., Frühwald MC; Swabian Childrens' Cancer Center, Childrens' Hospital Augsburg and EU-RHAB Registry, Augsburg, Germany., Kool M; German Cancer Consortium (DKTK), Core Center Heidelberg, Heidelberg, Germany.; Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.
Jazyk: angličtina
Zdroj: Acta neuropathologica [Acta Neuropathol] 2016 Jul; Vol. 132 (1), pp. 149-51. Date of Electronic Publication: 2016 Apr 11.
DOI: 10.1007/s00401-016-1574-9
Databáze: MEDLINE