Antiretroviral Drug Resistance Among Children and Youth in the United States With Perinatal HIV.

Autor:	Van Dyke RB; Department of Pediatrics, Tulane University School of Medicine, New Orleans, Louisiana., Patel K; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Kagan RM; Focus Diagnostics, a Quest Diagnostics Subsidiary, San Juan Capistrano, California., Karalius B; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Traite S; Center for Biostatistics in AIDS Research, Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Meyer WA 3rd; Quest Diagnostics, Baltimore, Maryland., Tassiopoulos KK; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Seage GR 3rd; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Seybolt LM; Department of Pediatrics, Louisiana State University Health Sciences Center, New Orleans., Burchett S; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts., Hazra R; Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland., Lurie RH, Yogev R, Sanders MA, Malee K, Hunter S, Shearer W, Paul M, Cooper N, Harris L, Purswani M, Baig M, Cintron A, Puga A, Navarro S, Garvie P, Blood J, Burchett S, Karthas N, Kammerer B, Wiznia A, Burey M, Nozyce M, Dieudonne A, Bettica L, Adubato S, Chen J, Bulkley MG, Ivey L, Grant M, Knapp K, Allison K, Wilkins M, Acevedo-Flores M, Rios H, Olivera V, Silio M, Jones M, Sirois P, Spector S, Norris K, Nichols S, McFarland E, Katai A, Dunn J, Paul S, Scott G, Bryan P, Willen E
Jazyk:	angličtina
Zdroj:	Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2016 Jul 01; Vol. 63 (1), pp. 133-137. Date of Electronic Publication: 2016 Apr 07.
DOI:	10.1093/cid/ciw213
Abstrakt:	Among 234 US youths with perinatal human immunodeficiency virus, 75% had antiretroviral resistance, substantially higher than that of the reference laboratory overall (36%-44%). Resistance to newer antiretrovirals and to all antiretrovirals in a class was uncommon. The only factor independently associated with future resistance was a higher peak viral load. (© The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail journals.permissions@oup.com.)
Databáze:	MEDLINE
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