Molecular epidemiology of canine picornavirus in Hong Kong and Dubai and proposal of a novel genus in Picornaviridae.

Autor: Woo PCY; State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, China; Department of Microbiology, The University of Hong Kong, Hong Kong, China; Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong, China; Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong, China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou 310006, China. Electronic address: pcywoo@hku.hk., Lau SKP; State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, China; Department of Microbiology, The University of Hong Kong, Hong Kong, China; Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong, China; Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong, China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou 310006, China., Choi GKY; Department of Microbiology, The University of Hong Kong, Hong Kong, China., Huang Y; Department of Microbiology, The University of Hong Kong, Hong Kong, China., Sivakumar S; Central Veterinary Research Laboratory, Dubai, United Arab Emirates., Tsoi HW; Department of Microbiology, The University of Hong Kong, Hong Kong, China., Yip CCY; Department of Microbiology, The University of Hong Kong, Hong Kong, China., Jose SV; Central Veterinary Research Laboratory, Dubai, United Arab Emirates., Bai R; Department of Microbiology, The University of Hong Kong, Hong Kong, China., Wong EYM; Department of Microbiology, The University of Hong Kong, Hong Kong, China., Joseph M; Central Veterinary Research Laboratory, Dubai, United Arab Emirates., Li T; Department of Microbiology, The University of Hong Kong, Hong Kong, China., Wernery U; Central Veterinary Research Laboratory, Dubai, United Arab Emirates. Electronic address: cvrl@cvrl.ae., Yuen KY; State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, China; Department of Microbiology, The University of Hong Kong, Hong Kong, China; Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong, China; Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong, China; Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Zhejiang University, Hangzhou 310006, China.
Jazyk: angličtina
Zdroj: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases [Infect Genet Evol] 2016 Jul; Vol. 41, pp. 191-200. Date of Electronic Publication: 2016 Apr 03.
DOI: 10.1016/j.meegid.2016.03.033
Abstrakt: Previously, we reported the discovery of a novel canine picornavirus (CanPV) in the fecal sample of a dog. In this molecular epidemiology study, CanPV was detected in 15 (1.11%) of 1347 canine fecal samples from Hong Kong and one (0.76%) of 131 canine fecal samples from Dubai, with viral loads 1.06×10(3) to 6.64×10(6) copies/ml. Complete genome sequencing and phylogenetic analysis showed that CanPV was clustered with feline picornavirus (FePV), bat picornavirus (BatPV) 1 to 3, Ia io picornavirus 1 (IaioPV1) and bovine picornavirus (BoPV), and this cluster was most closely related to the genera Enterovirus and Sapelovirus. The Ka/Ks ratios of all the coding regions were <0.1. According to the definition of the Picornavirus Study Group of ICTV, CanPV, FePV, BatPV 1 to 3, IaioPV1 and BoPV should constitute a novel genus in Picornaviridae. BEAST analysis showed that this genus diverged from its most closely related genus, Sapelovirus, about 49 years ago.
(Copyright © 2016 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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