Reversible cerebral vasoconstriction syndromes and primary angiitis of the central nervous system: clinical, imaging, and angiographic comparison.

Autor: Singhal AB; Massachusetts General Hospital and Harvard Medical School, Boston, MA., Topcuoglu MA; Massachusetts General Hospital and Harvard Medical School, Boston, MA.; Neurology Department, Hacettepe University Hospitals, Ankara, Turkey., Fok JW; Department of Medicine, Yan Chai Hospital, Hong Kong, China., Kursun O; Neurology Clinic, Ankara Numune Education and Research Hospital, Ankara, Turkey., Nogueira RG; Grady Memorial Hospital and Emory University School of Medicine, Atlanta, GA., Frosch MP; Massachusetts General Hospital and Harvard Medical School, Boston, MA., Caviness VS Jr; Massachusetts General Hospital and Harvard Medical School, Boston, MA.
Jazyk: angličtina
Zdroj: Annals of neurology [Ann Neurol] 2016 Jun; Vol. 79 (6), pp. 882-94. Date of Electronic Publication: 2016 Apr 28.
DOI: 10.1002/ana.24652
Abstrakt: Reversible cerebral vasoconstriction syndromes (RCVS) and primary angiitis of the central nervous system (PACNS) are invariably considered in the differential diagnosis of new cerebral arteriopathies. However, prompt and accurate diagnosis remains challenging. Here we compared the features of 159 RCVS to 47 PACNS patients and developed criteria for prompt bedside diagnosis. Recurrent thunderclap headache (TCH), and single TCH combined with either normal neuroimaging, border zone infarcts, or vasogenic edema, have 100% positive predictive value for diagnosing RCVS or RCVS-spectrum disorders. In patients without TCH and positive angiography, neuroimaging can discriminate RCVS (no lesion) from PACNS (deep/brainstem infarcts). Ann Neurol 2016;79:882-894.
(© 2016 American Neurological Association.)
Databáze: MEDLINE
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