Linezolid-induced serotonin toxicity in a patient not taking monoamine oxidase inhibitors or serotonin receptor antagonists.

Autor:	Sutton J; Department of Medicine, Oklahoma State University Medical Center, Tulsa, Oklahoma (Sutton); and Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma (Stroup, Som)., Stroup J; Department of Medicine, Oklahoma State University Medical Center, Tulsa, Oklahoma (Sutton); and Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma (Stroup, Som)., Som M; Department of Medicine, Oklahoma State University Medical Center, Tulsa, Oklahoma (Sutton); and Oklahoma State University Center for Health Sciences, Tulsa, Oklahoma (Stroup, Som).
Jazyk:	angličtina
Zdroj:	Proceedings (Baylor University. Medical Center) [Proc (Bayl Univ Med Cent)] 2016 Apr; Vol. 29 (2), pp. 214-5.
DOI:	10.1080/08998280.2016.11929423
Abstrakt:	Linezolid is an oxazolidinone antibiotic with weak monoamine oxidase (MAO) type A and MAO type B inhibitory effects. Linezolid has been associated with serotonin toxicity when used concomitantly with multiple medications that are known to increase serotonin concentrations. We report the case of a 65-year-old woman with signs and symptoms of serotonin toxicity following administration of linezolid for treatment of methicillin-resistant Staphylococcus aureus pneumonia.
Databáze:	MEDLINE
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