COMPARATIVE MACROSCOPIC STUDY OF OSTEOCHONDRAL DEFECTS PRODUCED IN FEMURS OF RABBITS REPAIRED WITH BIOPOLYMER GEL CANE SUGAR.

Autor:	de Albuquerque PC; PhD. Professor in the Department of Surgery, Federal University of Pernambuco, Recife, PE, Brazil., Dos Santos SM; PhD. Professor in the Department of Surgery, Federal University of Pernambuco, Recife, PE, Brazil., de Andrade Aguiar JL; PhD. Professor in the Department of Surgery, Federal University of Pernambuco, Recife, PE, Brazil., Filho NP; Professor in the Department of Pathology, Federal University of Pernambuco, Recife, PE, Brazil., de Mello RJ; Professor in the Department of Pathology, Federal University of Pernambuco, Recife, PE, Brazil., Costa ML; Professor in the Department of Pathology, Federal University of Pernambuco, Recife, PE, Brazil., de Albuquerque Olbertz CM; Medical Student at the Federal university of Pernambuco, Recife, PE, Brazil., de Souza Almeida TM; Medical Student at the Federal university of Pernambuco, Recife, PE, Brazil., da Silva Santos AH; Assistant Professor in the Department of Accounting and Actuarial Sciences, Federal University of Pernambuco, Recife, PE, Brazil., da Silva JC; Neurosurgeon at Hospital das Clínicas, Federal University of Pernambuco, Recife, PE, Brazil.
Jazyk:	angličtina
Zdroj:	Revista brasileira de ortopedia [Rev Bras Ortop] 2015 Dec 06; Vol. 46 (5), pp. 577-84. Date of Electronic Publication: 2015 Dec 06 (Print Publication: 2011).
DOI:	10.1016/S2255-4971(15)30415-8
Abstrakt:	Objective: To study the surface, coloring, consistency, continuity and healing of osteochondral defects produced in the femoral condyles of rabbits and filled with sugar cane biopolymer gel (SCBG), after 90, 120 and 180 days, and in comparison with a control group. Method: Sixteen adult New Zealand white rabbits aged 6 to 7 months, weighing between 2 and 2.5 kg and without locomotor system abnormalities were studied. In all the animals, a defect was made in the femoral condyles of the right and left knees, measuring 3.2 mm in diameter and 4 mm in depth, using a trephine. The animals were divided into two groups: study group formed by the right knees, in which the medial and lateral condyles received implants of SCBG; and control group formed by the left knees, in which the medial and lateral condyles were allowed to heal naturally. The knees were assessed 90, 120 and 180 days after the operation. After the animals had been sacrificed, the anatomical specimens were resected and placed in Bouin's solution. They were then photographed with a Nikon Coolpix 5400(®) coupled to a Nikon SM2800(®) stereoscopic loupe, to analyze the surface, coloring, consistency, continuity and healing. Results: The results were evaluated using the chi-square test. There were no significant differences in the macroscopic assessments of healing between the study and control groups. Conclusion: With regard to the surface, coloring, consistency, continuity and healing of the defects, the macroscopic appearance of the tissue repaired with SCBG was similar to that of the control group.
Databáze:	MEDLINE
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