Serial assessment of right ventricular systolic function in patients with precapillary pulmonary hypertension using simple echocardiographic parameters: A comparison with cardiac magnetic resonance imaging.

Autor: Spruijt OA; Department of Pulmonary Medicine, VU University Medical Center, Amsterdam, The Netherlands., Di Pasqua MC; Department of Pulmonary Medicine, VU University Medical Center, Amsterdam, The Netherlands; Department of Cardiology, Ferrarotto Hospital, University of Catania, Catania, Italy., Bogaard HJ; Department of Pulmonary Medicine, VU University Medical Center, Amsterdam, The Netherlands., van der Bruggen CE; Department of Pulmonary Medicine, VU University Medical Center, Amsterdam, The Netherlands., Oosterveer F; Department of Pulmonary Medicine, VU University Medical Center, Amsterdam, The Netherlands., Marcus JT; Department of Physics and Medical Technology, VU University Medical Center, Amsterdam, The Netherlands., Vonk-Noordegraaf A; Department of Pulmonary Medicine, VU University Medical Center, Amsterdam, The Netherlands. Electronic address: a.vonk@vumc.nl., Handoko ML; Department of Cardiology, VU University Medical Center, Amsterdam, The Netherlands.
Jazyk: angličtina
Zdroj: Journal of cardiology [J Cardiol] 2017 Jan; Vol. 69 (1), pp. 182-188. Date of Electronic Publication: 2016 Mar 22.
DOI: 10.1016/j.jjcc.2016.02.019
Abstrakt: Background: Although cardiac magnetic resonance imaging (CMRI) is the gold standard for the (serial) assessment of right ventricular (RV) function, the technique has several drawbacks: CMRI is relatively expensive, has a limited availability, and the analyses are time consuming. Echocardiography (echo) can overcome several of these issues. The aim of this study was to compare simple echo-derived parameters of RV systolic function with CMRI-derived RV ejection fraction (RVEF) in patients with precapillary pulmonary hypertension (PH) and to determine which echo parameters best followed the change in CMRI-derived-RVEF during follow-up.
Methods: CMRI and echo were performed in 96 precapillary PH patients. In 38 patients a second set of a CMRI and echo were available. Retrospectively, echo-derived right ventricular fractional area change (RVFAC), tricuspid annulus plane systolic excursion (TAPSE), fractional transversal (FTWM), and longitudinal wall motion (FLWM) were assessed and compared with CMRI-derived-RVEF. Furthermore, the changes in RVFAC, TAPSE, FTWM, and FLWM during follow-up were compared with the change in CMRI-derived-RVEF.
Results: All four echo parameters were significantly correlated to CMRI-derived-RVEF. The strongest relationship was seen between CMRI-derived-RVEF and RVFAC (r 2 =0.567). However, sensitivity for predicting a deterioration in CMRI-derived RVEF was poor for all four echo-derived parameters (ranging from 33% to 56%).
Conclusions: Although RVFAC, TAPSE, FTWM, and FLWM were significantly correlated to CMRI-derived-RVEF, all four echo parameters showed a low sensitivity for predicting a deterioration in CMRI-derived RVEF during follow-up. Therefore, RVFAC, TAPSE, FTWM, and FLWM are not suitable parameters for the serial assessment of RV systolic function in patients with precapillary PH.
(Copyright © 2016 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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