Mutations of TP53 gene in adult acute lymphoblastic leukemia at diagnosis do not affect the achievement of hematologic response but correlate with early relapse and very poor survival.

Autor: Salmoiraghi S; Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy., Montalvo ML; Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy., Ubiali G; Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy., Tosi M; Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy., Peruta B; Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy., Zanghi P; Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy., Oldani E; Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy., Boschini C; Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy., Kohlmann A; Personalized Healthcare and Biomarkers, Innovative Medicines and Early Development, AstraZeneca, Cambridge, UK., Bungaro S; Centro Ricerche Tettamanti, Clinica Pediatrica Università Milano-Bicocca, Ospedale San Gerardo, Monza, Italy., Intermesoli T; Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy., Terruzzi E; Divisione di Ematologia e Trapianto di Midollo Osseo, Ospedale San Gerardo, Monza, Italy., Angelucci E; Ematologia e Centro Trapianti, Ospedale Oncologico di Riferimento Regionale 'Armando Businco', Azienda Ospedaliera 'Brotzu', Cagliari, Italy., Cavattoni I; Ematologia e Centro Trapianti di Midollo Osseo, Ospedale Centrale, Bolzano, Italy., Ciceri F; Hematology, IRCCS San Raffaele Scientific Institute, Milano, Italy., Bassan R; Hematology, Ospedale dell'Angelo, Mestre-Venezia, Italy., Rambaldi A; Dipartimento Scienze Cliniche e di Comunità, University of Milan, Italy Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy arambaldi@asst-pg23.it., Spinelli O; Hematology and Bone Marrow Transplant Unit of Azienda Ospedaliera Papa Giovanni XXIII, Bergamo, Italy.
Jazyk: angličtina
Zdroj: Haematologica [Haematologica] 2016 Jun; Vol. 101 (6), pp. e245-8. Date of Electronic Publication: 2016 Mar 18.
DOI: 10.3324/haematol.2015.137059
Databáze: MEDLINE