[MRI-characteristics of epileptogenic supratentorial brain tumors in children].

Autor:	Khalilov VS; FGBUZ 'Tsentral'naja detskaja klinicheskaja bol'nitsa' FMBA Rossii, Moskva., Kholin AA; GBOU VPO 'Rossijskij natsional'nyj issledovatel'skij meditsinskij universitet im. N.I. Pirogova' Minzdrava RF, Moskva; FGBU 'Rossijskaja detskaja klinicheskaja bol'nitsa' Minzdrava RF, Moskva., Medvedeva NA; FGBUZ 'Tsentral'naja detskaja klinicheskaja bol'nitsa' FMBA Rossii, Moskva., Vasiliev IG; FGBU 'Rossijskaja detskaja klinicheskaja bol'nitsa' Minzdrava RF, Moskva., Rasskazchikova IV; FGBU 'Rossijskaja detskaja klinicheskaja bol'nitsa' Minzdrava RF, Moskva., Ismailova RR; GBOU VPO 'Rossijskij natsional'nyj issledovatel'skij meditsinskij universitet im. N.I. Pirogova' Minzdrava RF, Moskva., Kislyakov AN; FGBU 'Morozovskaja detskaja gorodskaja klinicheskaja bol'nitsa' Departamenta zdravoohranenija Moskvy, Moskva., Demushkina AA; FGBU 'Rossijskaja detskaja klinicheskaja bol'nitsa' Minzdrava RF, Moskva., Alikhanov AA; FGBU 'Rossijskaja detskaja klinicheskaja bol'nitsa' Minzdrava RF, Moskva.
Jazyk:	ruština
Zdroj:	Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova [Zh Nevrol Psikhiatr Im S S Korsakova] 2016; Vol. 116 (1), pp. 56-63.
DOI:	10.17116/jnevro20161161156-63
Abstrakt:	Objective: To analyze MR-images in patients with symptomatic epilepsy associated with the brain tumor. Material and Methods: MRI results of 52 patients with symptomatic epilepsy operated for tumors of supratentorial localization were analyzed. The most epileptogenic tumors with atypical MRI signs and subtle clinical presentation were identified. All patients with tumors were operated using different methods of surgical intervention. Results: Dysembryoplastic neuroepithelial tumors (DNET), diffuse astrocytomas (DA) and gangliogliomas (GG) were the most frequent epileptogenic tumors. In all the cases of DNET and in 4 patients with GG, epileptic seizures were the first, and in 4 of 5 cases of DIO were the only clinical sign of tumor presence. In DNET, DA and GG, there was an iso- or hypointensive signal on T1 WI and a signal varying in intensity from moderate to hyperintense in T2 and FLAIR WI, while in cases with DNET and GG, no mass effect and perifocal edema was practically seen. The so-called «spume-like» (multicystic) structure was most clearly observed in FLAIR WI. No significant changes in the dimensions of the DNET and GG were identified. The combination of DNET with focal cortical dysplasia was noted in one case. In DA, it was difficult to distinguish the perifocal edema from tumorous tissue and normal brain tissues, and the growth potential of malformation was slow. Conclusion: Epileptogenic tumors can imitate the x-ray characteristics of each other, and mimicry to gangliogliomas, oligodendrogliomas and astrocytomas Gr I, II, and others. They are the most frequent causes of symptomatic focal epilepsy. The presence of these malformations is necessary to exclude first of all in all cases of pharmacoresistant epilepsy.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu