[Para-infectious seizures: A retrospective multicentre study].
| Autor: | Conejo Moreno D; Hospital Universitario de Burgos, Burgos, España. Electronic address: dconejo@saludcastillayleon.es., Rodríguez Fernández C; Hospital Universitario de León, León, España., Ruíz Ayúcar de la Vega I; Hospital Universitario de Salamanca, Salamanca, España., Ortiz Madinaveitia S; Hospital Santa Bárbara de Soria, Soria, España., Hedrera Fernández A; Hospital Universitario Río Hortega, Valladolid, España., Maldonado Ruiz E; Hospital Rio Carrión de Palencia, Palencia, España., Hernández Fabian A; Hospital Universitario de Salamanca, Salamanca, España., Hortigüela Saeta MM; Hospital Universitario de Burgos, Burgos, España., Cancho Candela R; Hospital Universitario Río Hortega, Valladolid, España. |
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| Jazyk: | Spanish; Castilian |
| Zdroj: | Anales de pediatria (Barcelona, Spain : 2003) [An Pediatr (Barc)] 2016 Dec; Vol. 85 (6), pp. 300-304. Date of Electronic Publication: 2016 Mar 07. |
| DOI: | 10.1016/j.anpedi.2016.01.023 |
| Abstrakt: | Introduction: Para-infectious seizures are afebrile seizures that are associated with mild infections, and occur in children with no pre-existing neurological illness. They are still little known in our environment. Methods: A multicentre retrospective study was conducted that included patients with normal psychomotor development and had presented with one or more seizures in the context of a mild afebrile infection. Results: A total of 38 patients (47% male, 53% female) were included in the study over a period of three years (2012-2015). The mean age was 2.1 years. A previous history of febrile seizures was found in 7.9% of them. Mean number of seizures per patient was 2.2, with 57.9% of them being tonic-clonic seizures. The mean duration of seizures was 3.2minutes. An EEG was performed during admission in 73.7% of cases. Lumbar punctures were performed in 34.2% of cases. All were normal. Neuroimaging tests were carried out in 36.9% of cases. Brain MRI was the imaging test performed in most cases (21.1%), with no any pathological findings. The most frequent infection found was acute gastroenteritis (68%), followed by upper respiratory tract infection (32%). Almost two-thirds (63.2%) of patients did not require anticonvulsant medication. Rectal diazepam was the most frequently used drug in emergencies. Intravenous medication was required by 28.9% of patients due to repeated seizures. The most frequently used drug in the non-emergency setting was valproic acid. Anticonvulsant treatment was continued after discharge in 16% of patients. Para-infectious seizures was the diagnosis in 76.3% of cases when discharged. Conclusions: Knowledge of para-infectious seizures, their clinical diagnosis and benign course is crucial, as this would avoid further testing and unnecessary treatments. (Copyright © 2015 Asociación Española de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.) |
| Databáze: | MEDLINE |
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