Electrocardiographic and Cardiac Autonomic Indices - Implications of Sex-Specific Risk Stratification in Women After Acute Myocardial Infarction.
| Autor: | Ubrich R, Barthel P, Berkefeld A, Hnatkova K, Huster KM, Dommasch M, Sinnecker D, Steger A, Schmidt G; Medizinische Klinik und Poliklinik I, Klinikum rechts der Isar, Technische Universität München, Ismaninger Strasse 22, München 81675, Germany. gschmidt@tum.de., Malik M |
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| Jazyk: | angličtina |
| Zdroj: | Current pharmaceutical design [Curr Pharm Des] 2016; Vol. 22 (25), pp. 3817-28. |
| DOI: | 10.2174/1381612822666160311115605 |
| Abstrakt: | Background: The debate on whether sex-specific predictive models improve risk stratification after myocardial infarction is ongoing. Methods: This review summarises the current clinical knowledge on sex-specific differences in post-infarction risk stratification parameters. Particular focus is given to electrocardiographic risk factors and indices of cardiac autonomic status. Results: Differences in the underlying pathophysiology between men and women are known. However, clinical findings often lead to uncertain conclusions for a number of risk predictors including, among others, resting heart rate, heart rate variability, heart rate turbulence, QT interval duration, and QRS-T angle. The review links recent findings in prognostic parameters with successful approaches in sex-specific non-invasive risk stratification. Conclusion: Disparities are described in the current clinical opinions on the relevance of investigated parameters in women and possible directions for further research in the field are given. |
| Databáze: | MEDLINE |
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