Post splenectomy related pulmonary hypertension.
Autor: | Palkar AV; Department of Pulmonary, Critical Care and Sleep Medicine, North Shore - LIJ Health System, New York, NY 11040, United States., Agrawal A; Department of Medicine, Monmouth Medical Center, Long Branch, NJ 07740, United States., Verma S; Department of Pulmonary, Critical Care and Sleep Medicine, North Shore - LIJ Health System, New York, NY 11040, United States., Iftikhar A; Department of Pulmonary, Critical Care and Sleep Medicine, North Shore - LIJ Health System, New York, NY 11040, United States., Miller EJ; Department of Pulmonary, Critical Care and Sleep Medicine, North Shore - LIJ Health System, New York, NY 11040, United States., Talwar A; Department of Pulmonary, Critical Care and Sleep Medicine, North Shore - LIJ Health System, New York, NY 11040, United States. |
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Jazyk: | angličtina |
Zdroj: | World journal of respirology [World J Respirol] 2015 Jul 28; Vol. 5 (2), pp. 69-77. |
DOI: | 10.5320/wjr.v5.i2.69 |
Abstrakt: | Splenectomy predisposes patients to a slew of infectious and non-infectious complications including pulmonary vascular disease. Patients are at increased risk for venous thromboembolic events due to various mechanisms that may lead to chronic thromboembolic pulmonary hypertension (CTEPH). The development of CTEPH and pulmonary vasculopathy after splenectomy involves complex pathophysiologic mechanisms, some of which remain unclear. This review attempts congregate the current evidence behind our understanding about the etio-pathogenesis of pulmonary vascular disease related to splenectomy and highlight the controversies that surround its management. |
Databáze: | MEDLINE |
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