Early intervention leads to long-term developmental improvements in very preterm infants, especially infants with bronchopulmonary dysplasia.

Autor: Van Hus J; Department of Rehabilitation, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands., Jeukens-Visser M; Department of Rehabilitation, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands., Koldewijn K; Department of Rehabilitation, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands., Holman R; Department of Medical Informatics, Amsterdam Medical Centre, University of Amsterdam, Amsterdam, The Netherlands., Kok JH; Department of Neonatology, Emma's Children's Hospital, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands., Nollet F; Department of Rehabilitation, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands., Van Wassenaer-Leemhuis AG; Department of Neonatology, Emma's Children's Hospital, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
Jazyk: angličtina
Zdroj: Acta paediatrica (Oslo, Norway : 1992) [Acta Paediatr] 2016 Jul; Vol. 105 (7), pp. 773-81. Date of Electronic Publication: 2016 Apr 22.
DOI: 10.1111/apa.13387
Abstrakt: Aim: Various early intervention programmes have been developed in response to the high rate of neurodevelopmental problems in very preterm infants. We investigated longitudinal effects of the Infant Behavioral Assessment and Intervention Program on cognitive and motor development of very preterm infants at the corrected ages of six months to five and a half years.
Methods: This randomised controlled trial divided 176 infants with a gestational age <32 weeks or birthweight <1500 g into intervention (n = 86) and control (n = 90) groups. Cognitive development and motor development were assessed with the Bayley Scales of Infant Development at the CAs of six, 12 and 24 months and at five and a half years with the Wechsler Preschool and Primary Scale of Intelligence and the Movement Assessment Battery for Children.
Results: We found significant longitudinal intervention effects (0.4 SD, p = 0.006) on motor development, but no significant impact on cognitive development (p = 0.063). Infants with bronchopulmonary dysplasia showed significant longitudinal intervention effects for cognitive (0.7 SD; p = 0.019) and motor (0.9 SD; p = 0.026) outcomes. Maternal education had little effect on intervention effects over time.
Conclusion: The Infant Behavioral Assessment and Intervention Program led to long-term developmental improvements in the intervention group, especially in infants with BPD.
(©2016 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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