Giant seminal vesicle cyst: an unusual site for a malignant extragastrointestinal stromal tumour.

Autor: Boaz RJ; Department of Urology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India., George AP; Department of Urology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India., Kumar RM; Department of Pathology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India., Devasia A; Department of Urology, Christian Medical College and Hospital, Vellore, Tamil Nadu, India.
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2016 Mar 02; Vol. 2016. Date of Electronic Publication: 2016 Mar 02.
DOI: 10.1136/bcr-2015-214066
Abstrakt: Mesenchymal tumours with clinicopathological and molecular profiles similar to gastrointestinal stromal tumours (GISTs) are, on occasion, found in extragastrointestinal locations. Extra GIST (EGIST) is a singular occurrence in the genitourinary tract. A 30-year-old man, catheterised following urinary retention, was found to have a complex pelvic retrovesical cyst on imaging. At operation, origin from the right seminal vesicle was evident with histopathology confirming a GIST. The patient received adjuvant therapy with tyrosine kinase inhibitor and is currently disease free at 2 years. This is only the second report of an EGIST at this anatomic locale. The current literature presents significant uncertainty in defining the true origin of EGISTs, particularly those in the pelvis. We propose the designation origin indeterminate stromal tumour (OIST), to facilitate disambiguation and advance accurate profiling of EGIST; a subject in evolution.
(2016 BMJ Publishing Group Ltd.)
Databáze: MEDLINE