Transplantation of Simian Mesenchymal Stem Cells to Baboons with Experimentally Induced Myocardial Infarction.

Autor: Agrba VZ; Research Institute of Medical Primatology, Sochi, Russia. agrba_vz@mail.ru., Porkhanov VA; Research Institute of Medical Primatology, Sochi, Russia., Karal-Ogly DD; Research Institute of Medical Primatology, Sochi, Russia., Leontyuk AV; Research Institute of Medical Primatology, Sochi, Russia., Kovalenko AL; Research Institute of Medical Primatology, Sochi, Russia., Sholin IY; Research Institute of Medical Primatology, Sochi, Russia., Gvozdik TE; Research Institute of Medical Primatology, Sochi, Russia., Ignatova IE; Research Institute of Medical Primatology, Sochi, Russia., Agumava AA; Research Institute of Medical Primatology, Sochi, Russia., Chuguev YP; Research Institute of Medical Primatology, Sochi, Russia., Gvaramiya IA; Research Institute of Medical Primatology, Sochi, Russia., Lapin BA; Research Institute of Medical Primatology, Sochi, Russia.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2016 Feb; Vol. 160 (4), pp. 589-91. Date of Electronic Publication: 2016 Feb 24.
DOI: 10.1007/s10517-016-3223-7
Abstrakt: Culture of mesenchymal stem cells isolated from the bone marrow of primates by their characteristics met the requirements of stem cells. It was shown that transplantation of allogeneic mesenchymal stem cells (2 million cells per 1 kg body weight) immediately after ligation of the left anterior descending coronary artery between the middle and upper thirds led to neovascularization and capillarization of the ischemic myocardium.
Databáze: MEDLINE
Externí odkaz: