Nasopharyngeal carriage of Streptococcus pneumoniae in adults infected with human immunodeficiency virus in Jakarta, Indonesia.

Autor:	Harimurti K; Clinical Epidemiology & Evidence-Based Medicine (CEEBM) Unit, Faculty of Medicine Univeritas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia., Saldi SR; Clinical Epidemiology & Evidence-Based Medicine (CEEBM) Unit, Faculty of Medicine Univeritas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia., Dewiasty E; Clinical Epidemiology & Evidence-Based Medicine (CEEBM) Unit, Faculty of Medicine Univeritas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; Department of Internal Medicine, Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia., Khoeri MM; Eijkman Institute for Molecular Biology, Jakarta, Indonesia., Yunihastuti E; Department of Internal Medicine, Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo Hospital, Jakarta, Indonesia; HIV Integrated Services, Cipto Mangunkusumo Hospital, Jakarta, Indonesia., Putri T; Faculty of Biology, Gajah Mada University, Yogyakarta, Indonesia., Tafroji W; Eijkman Institute for Molecular Biology, Jakarta, Indonesia., Safari D; Eijkman Institute for Molecular Biology, Jakarta, Indonesia. Electronic address: safari@eijkman.go.id.
Jazyk:	angličtina
Zdroj:	Journal of infection and public health [J Infect Public Health] 2016 Sep-Oct; Vol. 9 (5), pp. 633-8. Date of Electronic Publication: 2016 Feb 16.
DOI:	10.1016/j.jiph.2016.01.004
Abstrakt:	This study investigated the distribution of serotype and antimicrobial susceptibility of Streptococcus pneumoniae carried by adults infected with human immunodeficiency virus (HIV) in Jakarta, Indonesia. Specimens of nasopharyngeal swab were collected from 200 HIV infected adults aged 21 to 63 years. Identification of S. pneumoniae was done by optochin susceptibility test and PCR for the presence of psaA and lytA genes. Serotyping was performed with sequential multiplex PCR and antibiotic susceptibility with the disk diffusion method. S. pneumoniae strains were carried by 10% adults with serotype 6A/B 20% was common serotype among cultured strains in 20 adults. Most of isolates were susceptible to chloramphenicol (80%) followed by clindamycin (75%), erythromycin (75%), penicillin (55%), and tetracycline (50%). This study found resistance to sulphamethoxazole/trimethoprim was most common with only 15% of strains being susceptible. High non-susceptibility to sulphamethoxazole/trimethoprim was observed in S. pneumoniae strains carried by HIV infected adults in Jakarta, Indonesia. (Copyright © 2016 King Saud Bin Abdulaziz University for Health Sciences. Published by Elsevier Ltd. All rights reserved.)
Databáze:	MEDLINE
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