Low-level laser therapy versus 5% amlexanox: a comparison of treatment effects in a cohort of patients with minor aphthous ulcers.

Autor: Jijin MJ; Department of Oral Medicine & Radiology, Coorg Institute of Dental Sciences, Virajpet, Coorg District, Karnataka State, India. Electronic address: Drjijin@gmail.com., Rakaraddi M; Professor and HOD, Department of Oral Medicine & Radiology, Coorg Institute of Dental Sciences, Virajpet, Coorg District, Karnataka State, India., Pai J; Professor, Department of Periodontics, Coorg Institute of Dental Sciences, Virajpet, Coorg District, Karnataka State, India., Jaishankar HP; Professor, Department of Oral Medicine & Radiology, JSS Dental College, Mysore, Karnataka State, India., Krupashankar R; Reader, Department of Oral Medicine & Radiology, Coorg Institute of Dental Sciences, Virajpet, Coorg District, Karnataka State, India., Kavitha AP; Senior Lecturer, Department of Oral Medicine & Radiology, Coorg Institute of Dental Sciences, Virajpet, Coorg District, Karnataka State, India., Anjana R; Medical officer ECHS, Virajpet, Coorg District, Karnataka State, India., Shobha R; Department of Oral Medicine & Radiology, Coorg Institute of Dental Sciences, Virajpet, Coorg District, Karnataka State, India.
Jazyk: angličtina
Zdroj: Oral surgery, oral medicine, oral pathology and oral radiology [Oral Surg Oral Med Oral Pathol Oral Radiol] 2016 Mar; Vol. 121 (3), pp. 269-73. Date of Electronic Publication: 2015 Dec 19.
DOI: 10.1016/j.oooo.2015.11.021
Abstrakt: Objective: The aim of the study was to compare the treatment effects of 5% amlexanox and low-level laser therapy (LLLT) in a cohort of patients who experienced minor aphthous stomatitis.
Study Design: A clinical trial was performed between 2012 and 2014 on 50 participants having minor aphthous ulcers. Group A participants were treated with amlexanox oral paste (lexanox 5% oral paste), and group B participants were treated with LLLT. Pain scores and sizes of ulcers were measured on the first, third, and seventh days of treatment in both groups. Data were analyzed using paired t test and independent t test.
Results: No significant difference was observed between the two groups with respect to pain level on the first and seventh days of treatment.
Conclusions: Both amlexanox and LLLT were equally effective in relieving pain associated with minor aphthous stomatitis. Both groups showed significant reduction in ulcer sizes and in pain scores.
(Copyright © 2016 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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