Molecular Pathology of Non-Small Cell Lung Cancer.
| Autor: | Serracino HS; Department of Pathology, University of Colorado Denver, 12631 E. 17th Avenue, Mail Stop B216, Aurora, CO 80045, USA., Franklin WA; Department of Pathology, University of Colorado Denver, 12631 E. 17th Avenue, Mail Stop B216, Aurora, CO 80045, USA., Aisner DL; Department of Pathology, University of Colorado Denver, 12631 E. 17th Avenue, Mail Stop B216, Aurora, CO 80045, USA. Electronic address: dara.aisner@ucdenver.edu. |
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| Jazyk: | angličtina |
| Zdroj: | Surgical pathology clinics [Surg Pathol Clin] 2012 Dec; Vol. 5 (4), pp. 903-18. Date of Electronic Publication: 2012 Sep 30. |
| DOI: | 10.1016/j.path.2012.08.006 |
| Abstrakt: | This review offers an overview of the molecular pathology of lung cancer, with a focus on analyses that are most commonly part of the current clinical testing paradigm. Molecular testing of lung cancer has proved integral to the success of new targeted therapies, and their use is now commonplace in treatment selection. Traditional pathologic evaluation, however, plays a major role in these advances and serves an equally critical role to aid in determining optimal therapy. (Published by Elsevier Inc.) |
| Databáze: | MEDLINE |
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