Acral melanocytic lesions in the United States: Prevalence, awareness, and dermoscopic patterns in skin-of-color and non-Hispanic white patients.

Autor: Madankumar R; Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York., Gumaste PV; Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York., Martires K; Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York., Schaffer PR; Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York., Choudhary S; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida., Falto-Aizpurua L; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida., Arora H; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida., Kallis PJ; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida., Patel S; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida., Damanpour S; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida., Sanchez MI; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida., Yin N; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida., Chan A; Department of Dermatology, Montefiore Medical Center, New York, New York., Sanchez M; Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York., Polsky D; Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York., Kanavy H; Department of Dermatology, Montefiore Medical Center, New York, New York; Department of Dermatology, St Barnabas Medical Center, New York, New York., Grichnik JM; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida., Stein JA; Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York. Electronic address: Jennifer.Stein@nyumc.org.
Jazyk: angličtina
Zdroj: Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2016 Apr; Vol. 74 (4), pp. 724-30.e1. Date of Electronic Publication: 2016 Jan 20.
DOI: 10.1016/j.jaad.2015.11.035
Abstrakt: Background: Acral lentiginous melanoma has increased mortality compared with other melanoma subtypes and disproportionately affects ethnic minorities. Acral melanocytic lesions have not been well studied in diverse populations of the United States.
Objective: We sought to assess the prevalence, awareness, and dermoscopic patterns of acral melanocytic lesions in skin-of-color and non-Hispanic white patients.
Methods: We prospectively examined the palms and soles of 1052 patients presenting to dermatology clinics in New York, NY, and Miami, FL, from October 2013 to April 2015.
Results: Acral melanocytic lesions were observed in 36% of our cohort. Skin-of-color patients were more likely to have acral melanocytic lesions than non-Hispanic white patients (P < .01). Acral melanocytic lesions correlated with increased mole counts, particularly on non-Hispanic white patients. The majority of lesions demonstrated benign dermoscopic patterns. We observed 2 lesions with the parallel ridge pattern in our cohort, both found to be atypical nevi on biopsy specimen. Patients often lacked awareness of the presence of their lesions.
Limitations: Interobserver variability in assessing dermoscopic patterns is a limitation.
Conclusions: Melanocytic lesions of the palms and soles are common, particularly in a cohort of multiple ethnicities from the United States. Dermoscopy of acral lesions is an important clinical tool for diagnosis and management of these lesions.
(Copyright © 2015 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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