Olfactory neuroblastoma: A case report.

Autor: Uslu GH; Department of Radiation Oncology, Faculty of Medicine, Kanuni Research and Education Hospital, Trabzon 61040, Turkey., Canyilmaz E; Department of Radiation Oncology, Faculty of Medicine, Karadeniz Technical University, Trabzon 61080, Turkey., Zengin AY; Department of Radiation Oncology, Faculty of Medicine, Kanuni Research and Education Hospital, Trabzon 61040, Turkey., Mungan S; Department of Pathology, Faculty of Medicine, Karadeniz Technical University, Trabzon 61080, Turkey., Yoney A; Department of Radiation Oncology, Faculty of Medicine, Karadeniz Technical University, Trabzon 61080, Turkey., Bahadir O; Department of Otorhinolaryngology, Faculty of Medicine, Karadeniz Technical University, Trabzon 61080, Turkey., Gocmez H; Department of Radiation Oncology, Faculty of Medicine, Kanuni Research and Education Hospital, Trabzon 61040, Turkey.
Jazyk: angličtina
Zdroj: Oncology letters [Oncol Lett] 2015 Dec; Vol. 10 (6), pp. 3651-3654. Date of Electronic Publication: 2015 Oct 20.
DOI: 10.3892/ol.2015.3821
Abstrakt: Olfactory neuroblastoma (ON) is a rare type of malignant neoplasm originating from the olfactory neuroepithelial cells of the nasal cavity. ON is also known as esthesioneuroblastoma or neuroendocrine carcinoma. The malignancy accounts for <3% of tumors originating in the nasal cavity. Through the nasal cavity, ON may infiltrate the sinuses, the orbit and the cranium. The tumor is characterized by a pattern of slow growth and local recurrences. Treatment options are surgical excision or surgery combined with a radiotherapy (RT) and/or chemotherapy combination treatment. The present study reports the case of a 69-year-old patient with a mass in the nasal cavity who was treated by combined surgical excision and RT. The literature for ON and the treatment of the tumor are also discussed.
Databáze: MEDLINE