Adherence to a Mediterranean diet is associated with reduced risk of heart failure in men.

Autor: Tektonidis TG; Unit of Nutritional Epidemiology, Institute of Environmental Medicine (IMM), Karolinska Institutet, Nobels väg 13, Box 210, SE-171 77, Stockholm, Sweden., Åkesson A; Unit of Nutritional Epidemiology, Institute of Environmental Medicine (IMM), Karolinska Institutet, Nobels väg 13, Box 210, SE-171 77, Stockholm, Sweden., Gigante B; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine (IMM), Karolinska Institutet, Stockholm, Sweden.; Division of Cardiovascular Medicine, Department of Clinical Sciences, Danderyd University Hospital, Stockholm, Sweden., Wolk A; Unit of Nutritional Epidemiology, Institute of Environmental Medicine (IMM), Karolinska Institutet, Nobels väg 13, Box 210, SE-171 77, Stockholm, Sweden., Larsson SC; Unit of Nutritional Epidemiology, Institute of Environmental Medicine (IMM), Karolinska Institutet, Nobels väg 13, Box 210, SE-171 77, Stockholm, Sweden.
Jazyk: angličtina
Zdroj: European journal of heart failure [Eur J Heart Fail] 2016 Mar; Vol. 18 (3), pp. 253-9. Date of Electronic Publication: 2016 Jan 18.
DOI: 10.1002/ejhf.481
Abstrakt: Aims: We examined the hypothesis that high adherence to a Mediterranean diet reduces the risk of developing heart failure (HF) as well as the risk of death from HF.
Methods and Results: The study population comprised 37 308 men from the Cohort of Swedish Men who were free from cardiovascular disease at baseline. The modified Mediterranean diet (mMED) score was created from a self-administered food frequency questionnaire, based on consumption of presumed beneficial/detrimental foods, on a 0-8 scale. Incident HF events were ascertained by linkage to the Swedish National Patient and the Cause of Death Registers. Relative risks (RR) with 95% confidence intervals (CI), adjusted for potential confounders, were estimated by Cox proportional hazards regression models. We identified 146 deaths from HF and 1269 incident HF events over a median follow-up of 10.9 years (1998-2008). The mMED score was inversely associated with risk of HF (multivariable RR for the highest vs. lowest quartile 0.69, 95% CI 0.57, 0.83); the corresponding RR of HF mortality was 0.55 (95% CI 0.31, 0.98). The multivariable RR for every two-point increment in the mMED score was 0.85 (95% CI 0.78, 0.91) for incidence of HF and 0.78 (95% CI 0.62, 0.98) for mortality from HF, respectively.
Conclusions: High adherence to a Mediterranean diet was associated with a lower risk of HF and mortality from HF in men. Further studies are needed to replicate these findings in other populations.
(© 2016 The Authors European Journal of Heart Failure © 2016 European Society of Cardiology.)
Databáze: MEDLINE
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