Investigation of Multisequence Magnetic Resonance Imaging for Detection of Recurrent Tumor After Transurethral Resection for Bladder Cancer.

Autor:	Rosenkrantz AB; From the Departments of *Radiology and †Pathology, and ‡Division of Urologic Oncology, Department of Urology, NYU School of Medicine, NYU Langone Medical Center, New York, NY., Ego-Osuala IO, Khalef V, Deng FM, Taneja SS, Huang WC
Jazyk:	angličtina
Zdroj:	Journal of computer assisted tomography [J Comput Assist Tomogr] 2016 Mar-Apr; Vol. 40 (2), pp. 201-5.
DOI:	10.1097/RCT.0000000000000363
Abstrakt:	Purpose: The aim of this study was to evaluate multisequence magnetic resonance imaging (MRI) in detecting local recurrence after transurethral resection for bladder cancer. Methods: Thirty-six patients with bladder cancer with previous transurethral resection underwent bladder MRI incorporating T2-weighted imaging, diffusion-weighted imaging, and delayed contrast-enhanced T1-weighted imaging, followed by cystoscopy. Two radiologists (R1 and R2) evaluated examinations for suspicious findings. Results: Forty-seven percent of patients had recurrent tumor at cystoscopy and biopsy. Using multisequence MRI, sensitivity and specificity were 67% and 81% for R1 and 73% and 62% for R2. Both readers missed 1 high-grade pathologic stage T1 recurrent tumor; otherwise, all missed tumors were low-grade pathologic stage Ta lesions. All false positives for R1 and 7 of 9 false positives for R2 were in patients receiving previous bacillus Calmette-Guerin therapy. Furthermore, 40% to 50% of solitary abnormalities and 83% to 100% of multifocal abnormalities were tumor recurrences; 12% to 20% of smooth wall thickening, 50% to 75% of irregular wall thickening, and 88% to 100% of papillary masses were tumor recurrences. Conclusions: Although multisequence MRI exhibited moderate performance for detecting recurrent tumor, nearly all missed tumors were low grade and noninvasive.
Databáze:	MEDLINE
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