Recent Strategies in Tissue Engineering for Guided Peripheral Nerve Regeneration.

Autor: Belanger K; Sorbonne University, Université de Technologie de Compiègne, CNRS, UMR 7338 Biomechanics and Bioengineering, Centre de Recherches Royallieu - CS 60 3019, 60203, Compiègne cedex, France., Dinis TM; Sorbonne University, Université de Technologie de Compiègne, CNRS, UMR 7338 Biomechanics and Bioengineering, Centre de Recherches Royallieu - CS 60 3019, 60203, Compiègne cedex, France., Taourirt S; Sorbonne University, Université de Technologie de Compiègne, CNRS, UMR 7338 Biomechanics and Bioengineering, Centre de Recherches Royallieu - CS 60 3019, 60203, Compiègne cedex, France., Vidal G; Sorbonne University, Université de Technologie de Compiègne, CNRS, UMR 7338 Biomechanics and Bioengineering, Centre de Recherches Royallieu - CS 60 3019, 60203, Compiègne cedex, France., Kaplan DL; Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA, 02155, USA., Egles C; Sorbonne University, Université de Technologie de Compiègne, CNRS, UMR 7338 Biomechanics and Bioengineering, Centre de Recherches Royallieu - CS 60 3019, 60203, Compiègne cedex, France.; Department of Oral and Maxillofacial Pathology, Tufts University, School of Dental Medicine, 55 Kneeland Street, Boston, MA, 02111, USA.
Jazyk: angličtina
Zdroj: Macromolecular bioscience [Macromol Biosci] 2016 Apr; Vol. 16 (4), pp. 472-81. Date of Electronic Publication: 2016 Jan 08.
DOI: 10.1002/mabi.201500367
Abstrakt: The repair of large crushed or sectioned segments of peripheral nerves remains a challenge in regenerative medicine due to the complexity of the biological environment and the lack of proper biomaterials and architecture to foster reconstruction. Traditionally such reconstruction is only achieved by using fresh human tissue as a surrogate for the absence of the nerve. However, recent focus in the field has been on new polymer structures and specific biofunctionalization to achieve the goal of peripheral nerve regeneration by developing artificial nerve prostheses. This review presents various tested approaches as well their effectiveness for nerve regrowth and functional recovery.
(© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.)
Databáze: MEDLINE
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