Short communication: The effect of genotyping cows to improve the reliability of genomic predictions for selection candidates.
| Autor: | Edel C; Institute of Animal Breeding, Bavarian State Research Center for Agriculture, 85586 Grub, Germany. Electronic address: Christian.Edel@LfL.bayern.de., Pimentel ECG; Institute of Animal Breeding, Bavarian State Research Center for Agriculture, 85586 Grub, Germany., Plieschke L; Institute of Animal Breeding, Bavarian State Research Center for Agriculture, 85586 Grub, Germany., Emmerling R; Institute of Animal Breeding, Bavarian State Research Center for Agriculture, 85586 Grub, Germany., Götz KU; Institute of Animal Breeding, Bavarian State Research Center for Agriculture, 85586 Grub, Germany. |
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| Jazyk: | angličtina |
| Zdroj: | Journal of dairy science [J Dairy Sci] 2016 Mar; Vol. 99 (3), pp. 1999-2004. Date of Electronic Publication: 2015 Dec 24. |
| DOI: | 10.3168/jds.2015-10246 |
| Abstrakt: | In this study we investigate the potential of enlarging the reference population for genomic prediction in dairy cattle by routinely genotyping a random sample of the first-crop daughters of every AI bull in the breeding program. We analyzed small nuclear pedigrees, each consisting of a genotyped selection candidate and 3 generations of genotyped male ancestors. Genotypes were taken from the genomic routine evaluation of Fleckvieh cattle in Germany and Austria. The phenotypic information of a daughter of any one male in each of these pedigrees was either considered to be part of the daughter yield deviation of the corresponding sire, or was assumed to be an individually observed genotyped daughter of this sire. Daughter genotypes in this case were simulated from phased haplotypes of their sires and random maternal gametes drawn from a haplotype library. We measured the gain from genotyping daughters as the increase in model-based theoretical reliability of the genomic prediction for a putative selection candidate. We expressed the improvements as a marginal increase, corresponding to an increase in reliability at a reliability baseline level of zero, to simplify comparisons. Results were encouraging with 2 to 40% of marginal reliability increase for selection candidates depending on the assumed heritability of the trait and the number of daughters modeled to be genotyped in the design. (Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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