Umbilical Artery Half-Peak Systolic Velocity Deceleration Time in Fetal Growth Restriction.

Autor: Bustos JC; Department of Obstetrics and Gynecology, San Juan de Dios Hospital, School of Medicine, University of Chile, Clinica Santa Maria, Santiago, Chile., Gonzalez V, Sepulveda W
Jazyk: angličtina
Zdroj: Fetal diagnosis and therapy [Fetal Diagn Ther] 2016; Vol. 40 (2), pp. 128-34. Date of Electronic Publication: 2015 Dec 23.
DOI: 10.1159/000442049
Abstrakt: Objective: To study the umbilical artery (UA) half-peak systolic velocity deceleration time (hPSV-DT) in pregnancies complicated by fetal growth restriction (FGR).
Methods: The study included 266 singleton, high-risk pregnancies with an estimated fetal weight <10th percentile, which were examined between 24 and 40 weeks' gestation and delivered within a week from the last ultrasound evaluation. UA hPSV-DT was measured with Doppler ultrasound in the same wave used to measure the pulsatility index. UA hPSV-DT values were correlated with perinatal outcome.
Results: UA hPSV-DT <5th percentile was found in 87 and 98% of fetuses with moderate and severe FGR, respectively. 94% of fetuses with a UA hPSV-DT <90 ms had poor perinatal outcome including perinatal death or prolonged admission to the neonatal intensive care unit. None of the fetuses had a UA hPSV-DT <70 ms. Perinatal death occurred in 39 fetuses; UA hPSV-DT was abnormal in all of them, with 95% of these fetuses having values of ≤120 ms. In the group of fetuses with absent/reverse end-diastolic velocity in the UA, the perinatal mortality rate was 51% for those with a UA hPSV-DT ≤90 ms and only 23% for those having a UA hPSV-DT >90 ms (p < 0.01).
Conclusions: UA hPSV-DT seems to be a useful technique in the evaluation of pregnancies at risk for FGR and perinatal death. Additionally, hPSV-DT was shown to be a good predictor of perinatal death, with values of <90 ms corresponding to imminent risk of intrauterine demise and values of <70 ms being likely to be incompatible with intrauterine life.
(© 2015 S. Karger AG, Basel.)
Databáze: MEDLINE