Calculation of standard liver volume in Korean adults with analysis of confounding variables.

Autor:	Um EH; Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Hwang S; Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Song GW; Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Jung DH; Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Ahn CS; Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Kim KH; Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Moon DB; Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Park GC; Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea., Lee SG; Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Jazyk:	angličtina
Zdroj:	Korean journal of hepato-biliary-pancreatic surgery [Korean J Hepatobiliary Pancreat Surg] 2015 Nov; Vol. 19 (4), pp. 133-8. Date of Electronic Publication: 2015 Nov 30.
DOI:	10.14701/kjhbps.2015.19.4.133
Abstrakt:	Backgrounds/aims: Standard liver volume (SLV) is an important parameter that has been used as a reference value to estimate the graft matching in living donor liver transplantation (LDLT). This study aimed to determine a reliable SLV formula for Korean adult patients as compared with the 15 SLV formulae from other studies and further estimate SLV formula by gender and body mass index (BMI). Methods: Computed tomography liver volumetry was performed in 1,000 living donors for LDLT and regression formulae for SLV was calculated. Individual donor data were applied to the 15 previously published SLV formulae, as compared with the SLV formula derived in this study. Analysis for confounding variables of BMI and gender was also performed. Results: Two formulae, "SLV (ml)=908.204×BSA-464.728" with DuBois body surface area (BSA) formula and "SLV (ml)=893.485×BSA-439.169" with Monsteller BSA formula, were derived by using the profiles of the 1,000 living donors included in the study. Comparison with other 15 other formulae, all except for Chouker formula showed the mean volume percentage errors of 4.8-5.4%. The gender showed no significant effect on total liver volume (TLV), but there was a significant increase in TLV as BMI increased. Conclusions: Our study suggested that most SLV formulae showed a crudely applicable range of SLV estimation for Korean adults. Considering the volume error in estimating SLV, further SLV studies with larger population from multiple centers should be performed to enhance its predictability. Our results suggested that classifying SLV formulae by BMI and gender is unnecessary.
Databáze:	MEDLINE
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