Severity of Periodontitis and Metabolic Syndrome: Is There an Association?

Autor: Gomes-Filho IS; Department of Health, Feira de Santana State University, Feira de Santana, Bahia, Brazil., das Mercês MC; Department of Health, Feira de Santana State University, Feira de Santana, Bahia, Brazil., de Santana Passos-Soares J; Department of Health, Feira de Santana State University, Feira de Santana, Bahia, Brazil.; Department of Preventive Dentistry, Federal University of Bahia, Salvador, Bahia, Brazil., Seixas da Cruz S; Department of Health, Feira de Santana State University, Feira de Santana, Bahia, Brazil.; Department of Epidemiology, Federal University of Recôncavo of Bahia, Santo Antonio de Jesus, Bahia, Brazil., Teixeira Ladeia AM; Bahiana School of Medicine and Public Health, Bahia Foundation for the Development of Sciences, Salvador, Bahia, Brazil., Trindade SC; Department of Health, Feira de Santana State University, Feira de Santana, Bahia, Brazil., de Moraes Marcílio Cerqueira E; Department of Health, Feira de Santana State University, Feira de Santana, Bahia, Brazil., Freitas Coelho JM; Department of Biological Sciences, Feira de Santana State University., Marques Monteiro FM; Department of Health, Feira de Santana State University, Feira de Santana, Bahia, Brazil., Barreto ML; Department of Epidemiology, Public Health Institute, Federal University of Bahia., Pereira Vianna MI; Department of Preventive Dentistry, Federal University of Bahia, Salvador, Bahia, Brazil., Nascimento Costa Mda C; Department of Epidemiology, Public Health Institute, Federal University of Bahia., Seymour GJ; Oral Molecular Immunopathology Research Group, Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Otago, New Zealand., Scannapieco FA; Department of Oral Biology, University of Buffalo, Buffalo, NY.
Jazyk: angličtina
Zdroj: Journal of periodontology [J Periodontol] 2016 Apr; Vol. 87 (4), pp. 357-66. Date of Electronic Publication: 2015 Dec 14.
DOI: 10.1902/jop.2015.150367
Abstrakt: Background: Metabolic syndrome (MetS) is a major factor for the occurrence of cardiovascular events. Causal factors for MetS are not well defined or yet unidentified. Preliminary investigations suggest that infections and inflammation may be involved in the etiology of this syndrome. This study aims to estimate the association between the severity of periodontitis (exposure) and MetS (outcome).
Methods: A cross-sectional study was conducted with 419 participants recruited from the Diabetes and Hypertensive Treatment Center, Feira de Santana, Bahia, Brazil. After administration of a questionnaire, general and oral clinical examination and laboratory tests were performed. Diagnosis of periodontitis and MetS was performed according to various criteria. The analysis of the effect of periodontitis on MetS used logistic regression analysis with adjustment for confounders.
Results: The prevalence of periodontitis was found to be between 34.61% and 55.37%, depending on the classification definitions used, and the prevalence of MetS ranged from 60.86% to 67.06%. In the group with periodontitis, 14.08% had severe and 41.29% had moderate levels of periodontitis. There was an association between severe periodontitis and MetS after adjustment for sex, age, household density, alcoholic beverage consumption, smoking habit, and cardiovascular disease (odds ratio ORadjusted_6 = 2.11, 95% confidence interval = 1.01 to 4.40, P = 0.05).
Conclusions: The results suggest that periodontitis is associated with MetS, and that MetS prevalence is related to severe periodontitis.
Databáze: MEDLINE
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