Exacerbations in neuroendocrine cell hyperplasia of infancy are characterized by increased air trapping.

Autor: Houin PR; Division of Pulmonary Medicine, Department of Pediatrics, University of Colorado, Aurora, Colorado.; Pulmonary Medicine, Department of Pediatrics, University of South Florida, Tampa, Florida., Deterding RR; Division of Pulmonary Medicine, Department of Pediatrics, University of Colorado, Aurora, Colorado., Young LR; Division of Pulmonary Medicine, Department of Pediatrics, Vanderbilt University, Nashville, Tennessee.
Jazyk: angličtina
Zdroj: Pediatric pulmonology [Pediatr Pulmonol] 2016 Mar; Vol. 51 (3), pp. E9-12. Date of Electronic Publication: 2015 Dec 07.
DOI: 10.1002/ppul.23347
Abstrakt: Neuroendocrine cell Hyperplasia of Infancy (NEHI) presents with tachypnea, retractions, hypoxemia, and often failure to thrive. The radiologic and physiologic findings in infants with NEHI have been well described with a distinct geographic pattern of ground-glass opacities on chest computerized tomography imaging and profound air-trapping on infant pulmonary function testing. Despite gradual improvement over time, unexplained exacerbation has been observed but not well characterized. We present physiological and radiological changes of increased air-trapping during acute exacerbations in two older children with NEHI who had previously experienced significant clinical improvement. These cases illustrate previously undescribed manifestations of NEHI in older children.
(© 2015 Wiley Periodicals, Inc.)
Databáze: MEDLINE
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