Catheter-based intervention for symptomatic patient with severe mitral regurgitation and very poor left ventricular systolic function - Safe but no room for complacency.

Autor: Loh PH; Poay Huan Loh, National University Heart Center Singapore, Singapore 169856, Singapore., Bourantas CV; Poay Huan Loh, National University Heart Center Singapore, Singapore 169856, Singapore., Chan PH; Poay Huan Loh, National University Heart Center Singapore, Singapore 169856, Singapore., Ihlemann N; Poay Huan Loh, National University Heart Center Singapore, Singapore 169856, Singapore., Gustafsson F; Poay Huan Loh, National University Heart Center Singapore, Singapore 169856, Singapore., Clark AL; Poay Huan Loh, National University Heart Center Singapore, Singapore 169856, Singapore., Price S; Poay Huan Loh, National University Heart Center Singapore, Singapore 169856, Singapore., Mario CD; Poay Huan Loh, National University Heart Center Singapore, Singapore 169856, Singapore., Moat N; Poay Huan Loh, National University Heart Center Singapore, Singapore 169856, Singapore., Alamgir F; Poay Huan Loh, National University Heart Center Singapore, Singapore 169856, Singapore., Estevez-Loureiro R; Poay Huan Loh, National University Heart Center Singapore, Singapore 169856, Singapore., Søndergaard L; Poay Huan Loh, National University Heart Center Singapore, Singapore 169856, Singapore., Franzen O; Poay Huan Loh, National University Heart Center Singapore, Singapore 169856, Singapore.
Jazyk: angličtina
Zdroj: World journal of cardiology [World J Cardiol] 2015 Nov 26; Vol. 7 (11), pp. 817-21.
DOI: 10.4330/wjc.v7.i11.817
Abstrakt: Many patients with left ventricular systolic dysfunction have concomitant mitral regurgitation (MR). Their symptoms and prognosis worsen with increasing severity of MR. Percutaneous MitraClip(®) can be used safely to reduce the severity of MR even in patients with advanced heart failure and is associated with improved symptoms, quality of life and exercise tolerance. However, a few patients with very poor left ventricular systolic function may experience significant haemodynamic disturbance in the peri-procedural period. We present three such patients, highlighting some of the potential problems encountered and discuss their possible pathophysiological mechanisms and safety measures.
Databáze: MEDLINE