The formation and design of the TRIAGE study--baseline data on 6005 consecutive patients admitted to hospital from the emergency department.

Autor: Plesner LL; Department of Cardiology, Endocrinology and Nephrology, North Zealand Hospital, Copenhagen University Hospital, Copenhagen, Denmark. louislindplesner@gmail.com.; Department of Cardiology, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark. louislindplesner@gmail.com., Iversen AK; Department of Cardiology, Endocrinology and Nephrology, North Zealand Hospital, Copenhagen University Hospital, Copenhagen, Denmark. annekristine89@gmail.com.; Department of Cardiology, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark. annekristine89@gmail.com., Langkjær S; Department of Cardiology, Endocrinology and Nephrology, North Zealand Hospital, Copenhagen University Hospital, Copenhagen, Denmark. sp.langkjaer@gmail.com.; Department of Cardiology, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark. sp.langkjaer@gmail.com., Nielsen TL; Department of Cardiology, Endocrinology and Nephrology, North Zealand Hospital, Copenhagen University Hospital, Copenhagen, Denmark. tureln@gmail.com.; Department of Cardiology, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark. tureln@gmail.com., Østervig R; Department of Cardiology, Endocrinology and Nephrology, North Zealand Hospital, Copenhagen University Hospital, Copenhagen, Denmark. rebeccaoestervig@hotmail.com.; Department of Cardiology, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark. rebeccaoestervig@hotmail.com., Warming PE; Department of Cardiology, Endocrinology and Nephrology, North Zealand Hospital, Copenhagen University Hospital, Copenhagen, Denmark. pederwarming@gmail.com.; Department of Cardiology, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark. pederwarming@gmail.com., Salam IA; Department of Cardiology, Endocrinology and Nephrology, North Zealand Hospital, Copenhagen University Hospital, Copenhagen, Denmark. idreessou@gmail.com.; Department of Cardiology, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark. idreessou@gmail.com., Kristensen M; Department of Cardiology, Endocrinology and Nephrology, North Zealand Hospital, Copenhagen University Hospital, Copenhagen, Denmark. kristensen.michael@gmail.com.; Department of Cardiology, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark. kristensen.michael@gmail.com., Schou M; Department of Cardiology, Endocrinology and Nephrology, North Zealand Hospital, Copenhagen University Hospital, Copenhagen, Denmark. m.schou@dadlnet.dk.; Department of Cardiology, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark. m.schou@dadlnet.dk., Eugen-Olsen J; Clinical Research Centre, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark. jespereugenolsen@gmail.com., Forberg JL; Emergency Department, North Zealand Hospital, Copenhagen University Hospital, Copenhagen, Denmark. Jakob.Lundager.Forberg@regionh.dk., Køber L; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. Lars.Koeber@regionh.dk., Rasmussen LS; Department of Anaesthesia, Centre of Head and Orthopaedics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark. lars.rasmussen.01@regionh.dk., Sölétormos G; Department of Clinical Biochemistry, North Zealand Hospital, Copenhagen University Hospital, Copenhagen, Denmark. georg.soeletormos@regionh.dk., Pedersen BK; Centre of Inflammation and Metabolism (CIM) and Centre for Physical Activity Research (CFAS), Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark. bente.klarlund.pedersen@regionh.dk., Iversen K; Department of Cardiology, Endocrinology and Nephrology, North Zealand Hospital, Copenhagen University Hospital, Copenhagen, Denmark. kasper.k.iversen@gmail.com.; Department of Cardiology, Herlev Hospital, Copenhagen University Hospital, Copenhagen, Denmark. kasper.k.iversen@gmail.com.
Jazyk: angličtina
Zdroj: Scandinavian journal of trauma, resuscitation and emergency medicine [Scand J Trauma Resusc Emerg Med] 2015 Dec 01; Vol. 23, pp. 106. Date of Electronic Publication: 2015 Dec 01.
DOI: 10.1186/s13049-015-0184-1
Abstrakt: Background: Patient crowding in emergency departments (ED) is a common challenge and associated with worsened outcome for the patients. Previous studies on biomarkers in the ED setting has focused on identification of high risk patients, and and the ability to use biomarkers to identify low-risk patients has only been sparsely examined. The broader aims of the TRIAGE study are to develop methods to identify low-risk patients appropriate for early ED discharge by combining information from a wide range of new inflammatory biomarkers and vital signs, the present baseline article aims to describe the formation of the TRIAGE database and characteristize the included patients.
Methods: We included consecutive patients ≥ 17 years admitted to hospital after triage staging in the ED. Blood samples for a biobank were collected and plasma stored in a freezer (-80 °C). Triage was done by a trained nurse using the Danish Emergency Proces Triage (DEPT) which categorizes patients as green (not urgent), yellow (urgent), orange (emergent) or red (rescusitation). Presenting complaints, admission diagnoses, comorbidities, length of stay, and 'events' during admission (any of 20 predefined definitive treatments that necessitates in-hospital care), vital signs and routine laboratory tests taken in the ED were aslo included in the database.
Results: Between September 5(th) 2013 and December 6(th) 2013, 6005 patients were included in the database and the biobank (94.1 % of all admissions). Of these, 1978 (32.9 %) were categorized as green, 2386 (39.7 %) yellow, 1616 (26.9 %) orange and 25 (0.4 %) red. Median age was 62 years (IQR 46-76), 49.8 % were male and median length of stay was 1 day (IQR 0-4). No events were found in 2658 (44.2 %) and 158 (2.6 %) were admitted to intensive or intermediate-intensive care unit and 219 (3.6 %) died within 30 days. A higher triage acuity level was associated with numerous events, including acute surgery, endovascular intervention, i.v. treatment, cardiac arrest, stroke, admission to intensive care, hospital transfer, and mortality within 30 days (p < 0.001).
Conclusion: The TRIAGE database has been completed and includes data and blood samples from 6005 unselected consecutive hospitalized patients. More than 40 % experienced no events and were therefore potentially unnecessary hospital admissions.
Databáze: MEDLINE
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