[Oxytocin in cesarean-sections. What's new?].

Autor: Yamaguchi ET; Hospital Universitário da Universidade de São Paulo (HU-USP), São Paulo, SP, Brasil. Electronic address: eduardo@hu.usp.br., Siaulys MM; Hospital e Maternidade Santa Joana, São Paulo, SP, Brasil., Torres ML; Departamento de Cirurgia, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, Brasil.
Jazyk: portugalština
Zdroj: Revista brasileira de anestesiologia [Rev Bras Anestesiol] 2016 Jul-Aug; Vol. 66 (4), pp. 402-7. Date of Electronic Publication: 2015 Nov 26.
DOI: 10.1016/j.bjan.2014.11.005
Abstrakt: Oxytocin is the uterotonic agent of choice in the prevention and treatment of postpartum uterine atony. Nevertheless, there is no consensus on the optimal dose and rate for use in cesarean sections. The use of high bolus doses (e.g., 10 IU of oxytocin) can determine deleterious cardiovascular changes for the patient, especially in situations of hypovolemia or low cardiac reserve. Furthermore, high doses of oxytocin for prolonged periods may lead to desensitization of oxytocin receptors in myometrium, resulting in clinical inefficiency.
(Copyright © 2015 Sociedade Brasileira de Anestesiologia. Publicado por Elsevier Editora Ltda. All rights reserved.)
Databáze: MEDLINE