Effect of 6-minute walk test on neuromuscular properties of patients with chronic obstructive pulmonary disease.

Autor: Pereira JS; Postgraduate Pulmonology Program, Federal University of Rio Grande do Sul, UFRGS., Lemos FA; Program of Human Movement Sciences, Faculty of Physical Education and Physiotherapy, Federal University of Rio Grande do Sul., Di Naso FC; Postgraduate Pulmonology Program, UFRGS.; Federal University of Rio Grande do Sul., Krüger R; Program of Human Movement Sciences, Faculty of Physical Education and Physiotherapy, Federal University of Rio Grande do Sul., de Oliveira A; Faculty of Physical Education and Physiotherapy, Federal University of Rio Grande do Sul., Knorst MM; Service of Pneumology, Hospital de Clinicas de Porto Alegre, Postgraduate Pulmonology Program, UFRGS., Dias AS; Postgraduate Program in Respiratory Sciences and Human Movement Sciences, UFRGS.; Physiotherapy Service of Hospital de Clinicas de Porto Alegre.
Jazyk: angličtina
Zdroj: The clinical respiratory journal [Clin Respir J] 2017 Nov; Vol. 11 (6), pp. 812-819. Date of Electronic Publication: 2015 Dec 28.
DOI: 10.1111/crj.12420
Abstrakt: Objective: The objective of this study was to evaluate the neuromechanical properties of the knee extensor muscles before and after the 6-minute walk test (6MWT) in chronic obstructive pulmonary disease (COPD) patients and control subjects.
Materials and Methods: COPD patients from the Department of Pulmonology of the Hospital de Clinicas de Porto Alegre and age- and sex-matched control volunteers without COPD were included in this study. Body composition and lower limb strength assessed by maximal voluntary isometric contraction (MVIC) of the knee extensors) were assessed before and after the 6MWT. The total reaction time (TRT), premotor time (PMT) and motor time (MT) were assessed using surface electromyography of the rectus femoris and vastus lateralis knee extensor muscles.
Results: Eighteen patients COPD patients (10 men, FEV 1 36 ± 12% of predicted) and 8 control subjects (5 men, FEV 1 82 ± 7% of predicted) were included. COPD patients had lower muscle strength before (21.77 ± 7.86 kg) and after the 6MWT (11.16 ± 4.70 kg) compared with control subjects (33.50 ± 14.01 kg before; 29.25 ± 16.66 kg after). After the 6MWT, COPD patients showed a significant reduction in the MVIC and a significant increase in the TRT and PMT, which did not occur in control subjects. The reaction time parameters were higher in COPD patients after the 6MWT compared with control subjects. The TRT (r = -0.535, P < 0.005) and PMT (r = -0.549, P < 0.005) were inversely correlated with the MVIC after the 6MWT.
Conclusions: Neuromuscular changes associated with upper motor neuron activation contribute to MVIC impairment in COPD patients after performing a functional test.
(© 2015 John Wiley & Sons Ltd.)
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje