| Autor: |
Peters SM; Department of Applied Physics, Eindhoven University of Technology, Postbus 513, 5600 MB Eindhoven, The Netherlands., Verheijen MA, Prins MW, Zijlstra P |
| Jazyk: |
angličtina |
| Zdroj: |
Nanotechnology [Nanotechnology] 2016 Jan 15; Vol. 27 (2), pp. 024001. Date of Electronic Publication: 2015 Nov 30. |
| DOI: |
10.1088/0957-4484/27/2/024001 |
| Abstrakt: |
Single metal nanoparticles are attractive biomolecular sensors. Binding of analyte to a functional particle results in a plasmon shift that can be conveniently monitored in a far-field optical microscope. Heterogeneities in spectral properties of individual particles in an ensemble affect the reliability of a single-particle plasmon sensor, especially when plasmon shifts are monitored in real-time using a fixed irradiation wavelength. We compare the spectral heterogeneity of different plasmon sensor geometries (gold nanospheres, nanorods, and bipyramids) and correlate this to their size and aspect-ratio dispersion. We show that gold bipyramids exhibit a strongly reduced heterogeneity in aspect ratio and plasmon wavelength compared to commonly used gold nanorods. We show that this translates into a significantly improved homogeneity of the response to molecular binding without compromising single-molecule sensitivity. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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